FEATURED EDITORIAL
We caught up with Melissa Murray, Ph.D., and Amy Rommel, Ph.D., to discuss tau-associated neurodegenerative diseases.
- Viral Coinfections: Emerging Challenges In Modern Drug Discovery
- Execution Debt In Early Drug Discovery: The Hidden Risk That Undermines Promising Biology
- Hope For Non-Hallucinogenic Neuroplastogens
- The Future Of Kidney Disease Therapeutics: Bringing Nanomedicine To Nephrology
- Injecting Cancer Killers: Intratumoral Therapy For Solid Tumors
- The Advantages Of Antibodies Over Ligands In The Alpha Emitter Era
- Proteomics Tools: A Resurrection
FEATURED APPLICATION CONTENT
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Explore how leveraging expert CDMO partnerships can streamline the development process and enhance the efficacy of your bispecific antibody therapies.
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Consider this alternative immunization approach — the PentaMice platform, a collection of five wildtype mouse strains bred in-house for increased MHC class II diversity — and how we're leveraging it for COVID-19 antibody discovery.
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By forging strategic partnerships with comprehensive CDMOs, see how emerging biopharma firms can navigate through early-phase development and ensure a smooth transition to clinical advancement.
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Explore how advanced single‑cell analysis links CAR localization, cell structure, and functional behavior, offering deeper insight into CAR T cell heterogeneity and performance.
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Gain insight into automating DNA size selection that shows how optimized bead ratios and programmable handling improve fragment recovery, consistency, and throughput.
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Gain insight into an automated high‑input workflow that streamlines long‑read whole‑genome library prep, supporting large DNA fragments while reducing reagent use.
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A streamlined workflow reduces reagent use and hands‑on time while preserving long‑read sequencing quality. See how multiplexed offer an efficient option for scaling or mobilizing sequencing efforts.
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Understanding covalent warhead kinetics is key to reducing safety risks early in discovery. Learn about a new approach to GSH‑based measurements that offers clearer predictors of toxicity.
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See how a rapid digital PCR workflow enables reliable detection of trace RCL levels while maintaining strong performance in complex samples, which support more confident decisions in manufacturing.
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Discover how mixed-mode chromatography enables high-yield purification of single-domain antibodies under mild conditions and why these approaches outperform traditional resins.
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Scalable lentiviral vector production is moving beyond adherent systems. Learn how streamlined workflows enable linear scale-up in stirred-tank bioreactors for cost-effective gene therapy manufacturing.
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Decoding immune cell interactions reveals critical insights for cancer therapy. Advanced imaging and spectral analysis enable precise identification of synapses, accelerating immuno-oncology research.
- Video Spotlight: Harvard's Alice Stanton On Engineering Integrated Human-Derived miBrain Organoid Models
- Insights From The Non-Opioid Pain Therapeutics Summit: Human-Centric Translational Models And The Reawakening Of Pain Pipelines
- Schrödinger's Equation Turns 100: How Quantum Chemistry Is Improving Drug Discovery
- Annual Reflections And Predictions From The Editors' Roundtable
- The Unlikely Weapon Against Fentanyl: Your Immune System
FEATURED NEWS HEADLINES
- Alloy Therapeutics Enters Into Agreement To Advance Novel Antibody Discovery Platform
- ADDF Launches New Phase Of $150M Diagnostics Accelerator Initiative To Power Next Generation Of Alzheimer's Precision Medicine Worldwide
- Scientists Find Promising Drug Target For Tuberculosis
- Dalriada Drug Discovery And Topos Bio Announce Collaboration To Advance Drug Discovery For Intrinsically Disordered Proteins
- Viva Biotech Accelerates AI-Driven Drug Discovery And Advance The 'Lab-In-The-Loop' With NVIDIA
- Cogent Biosciences Announces FDA Acceptance Of New Drug Application For Bezuclastinib In Patients With NonAdvanced Systemic Mastocytosis (NonAdvSM)
- Pattern Discovers New microRNA Drug For Treatment Of Glioblastoma Cancer
- Biophytis-LynxKite Alliance Expands To Turbocharge AI-Driven Drug Discovery For Next Generation Longevity Therapeutics
- PRISM BioLab And Receptor.AI Announce Drug Discovery Collaboration Agreement
- Queen Mary: Improving The Drug Development Pipeline
ARCHIVED NEWSLETTER
- 03.17.26 -- Hibernating Squirrels May Hold Clues To Treating Heart Failure
- 03.07.26 -- Drug Discovery Online Best Of February
- 03.03.26 -- In Vivo LNP-Engineered Cytokine-Armored CAR Cells For Solid Tumors
- 02.24.26 -- Small Molecule Enzyme Mimetics In Age-Related Neurodegeneration
- 02.17.26 -- Avoiding Protein Purification Artifacts That Still Undermine Drug Design