Drug Discovery App CS WP

  1. AAV Full/Empty Capsid Separation Using Mechanistic Modeling 5/1/2023

    In this study, we used mechanistic modeling to investigate how AAV-resin interactions are affected when MgCl2 is used as an elution additive.

  2. Optimizing A HIC Step With HTPD 5/1/2023

    A step-by-step high-throughput process development (HTPD) workflow to determine the optimal resin and initial conditions for hydrophobic interaction chromatography (HIC).

  3. Alkaline Stability Of Fc And VH3 Binding In Protein A Resins 5/1/2023

    In this study, we looked at how different antibody binding sites of a protein A ligand are affected by cleaning in place (CIP).

  4. Manufacturing Custom CDM With Precision Accuracy 4/10/2023

    Discover a novel approach for manufacturing chemically defined media with precision control of trace impurities that utilizes innovative raw material analysis, data analytics, and a proprietary algorithm.

  5. How Can The Industry Drive Down The Cost Of Viral Gene Therapies? 4/5/2023

    This article discusses how a combination of optimizing your process development, and process intensification can help drive the cost of dose down.

  6. Depth Filtration Devices For Cell Cultures, Fermentation Broths, And Cell Lysates 3/27/2023

    Typically, devices containing depth media filters can offer more efficient filtration. Browse depth filtration products and devices for the downstream processing of cell culture solutions, fermentation broths, and lysates.

  7. Partnering On An Innovative Hydrogel-Based Treatment For Glioblastoma 3/22/2023

    Treatments for glioblastoma multiforme (GBM) are in high demand. Learn more about the new possibilities for increased dosing and diffusion capabilities offered by nanoformed APIs.

  8. A Novel Downstream Processing System For Cell Line Development Workflows 3/21/2023

    A novel downstream processing system was developed to mitigate the downstream processing bottleneck in cell line development. Evaluate the performance of this innovative system in a mAb production process.

  9. Performance Of A Fully Automated, Single-Use TFF System In ADC Processes 3/21/2023

    Antibody-drug conjugates (ADCs) represent a significant area of growth in the biopharmaceutical industry. Explore the capabilities of a highly scalable, productive platform to streamline ADC production processes.

  10. Addressing New Challenges In Bulk Drug Substance Management 3/21/2023

    The first line of defense against cold chain failures is the integrity of freezing containers during storage and shipping. Explore "robust by design" single-use solutions in cold chain management.