Drug Discovery App CS WP
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Harmonizing Regulatory Guidelines For Assay Validation
7/24/2024
Explore a detailed process for validating ligand-binding assays, particularly for Fcγ receptor binding analytes or other structural isoforms.
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TFF Cassettes With 100 kDa Membranes For RNA And LNP Applications
7/3/2024
Explore data showcasing the performance of regenerated cellulose flat sheet membranes with a 100 kDa molecular weight cutoff for UF/DF of RNA molecules by TFF.
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Media And Buffer Mixing Using The Xcellerex™ Magnetic Mixer
6/19/2024
A common requirement for media and buffer preparation in biopharma processing is powder-liquid mixing. Review the performance of a 3000 L single-use mixing system for preparing aqueous solutions.
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Determining The Power Numbers For A Single-Use Mixing System
6/19/2024
In designing a mixing process for scale-up, the power number is a critical parameter. Explore the determined power numbers for a single-use mixer at various mixing speeds and fill levels.
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Automated Cell Washing And Formulation In CAR T Cell Therapy Manufacturing
6/14/2024
Explore data collected from a study utilizing healthy donors in a typical CAR T cell processing workflow without a transduction step from a cross-site validation study.
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Revolutionizing Drug Discovery From "Undruggables" To AI
6/10/2024
Explore four current trends in drug discovery, how each trend addresses some of the most crucial challenges in drug discovery, and the obstacles to their widespread adoption.
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A Hybrid Modeling Approach To Accelerate Media And Feed Development
6/7/2024
Explore the outcomes of a study focusing on building a mechanistic model to determine the growth kinetics of a CHO-based process producing a mAb.
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Considerations For Developing The Recirculation/Perfusion Process
6/6/2024
Learn about the recirculation and perfusion processes made possible by single-use, fixed-bed bioreactors designed for scaling up adherent cell culture processes.
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A Solution For The Scale-Up Of Multi-Column Chromatography
6/3/2024
Explore results from a study scaling up a monoclonal antibody (mAb) capture process utilizing the Resolute® BioSMB platform.
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CHO Media Screeing Success Using Benchmarking Studies
6/3/2024
Explore the challenges of media screening and a straightforward approach for saving time, reducing risks, and improving outcomes.