Drug Discovery App CS WP

1. A Transient Cell Line To Produce rAAV With Low-Level hcDNA Encapsidation 1/15/2025

   Discover the ability of a novel HEK293 suspension cell line for efficient and scalable rAAV production across various serotypes with low encapsidated host cell DNA levels.

2. Assessing The Safety Of Novel Therapeutics For Pediatric Indications 1/9/2025

   Discover strategies to overcome the challenges of nonclinical testing for pediatric and rare disease therapies, ensuring regulatory compliance and successfully advancing your medicinal products to the clinic.

3. Safety Assessment Of Intravitreal Implants In Dutch Belted Rabbits 1/9/2025

   Address unique anatomical challenges to deliver reliable, IND-enabling data for innovative therapies by relying on our expertise to design and execute your complex ocular safety study.

4. Nanosuspension Formulation To Maximize Potency For Preclinical Studies 1/9/2025

   By having a tailored proactive drug development approach, companies can accelerate their API's journey through preclinical development, ensuring the creation of a stable, high-potency formulation.

5. Overcoming Known Pharmacological Effects 1/9/2025

   Uncover how our team was able to address the challenges of evaluating treatments that reduce food consumption and cause body weight loss while ensuring animal health and study integrity.

6. Gene Therapy And Stem Cell Transplantation Via MRI-Guided Intraparenchymal Delivery Into Brain Regions 1/9/2025

   This stem cell transplantation technique, using real-time MRI imaging and precise stereotactic guidance, ensures accurate treatment delivery in macaque models for optimal brain region targeting.

7. Characterization Of The Sinclair Nanopig™ For Biopharmaceuticals Safety Assessment 1/9/2025

   Discover how the Sinclair Nanopig™ is transforming preclinical research and drug safety assessment to advance the future of translational science.

8. Advancing Drug Safety And Improving R&D Productivity With The Liver-Chip S1 12/10/2024

   Explore how the Emulate Liver-Chip S1 revolutionizes predictive toxicology by mimicking human liver biology, achieving superior sensitivity and specificity.

9. Depth Filters For The Clarification Of AAV 11/27/2024

   Explore study results demonstrating the ability of Sartoclear® depth filters to deliver high performance for AAV clarification, ensuring scalability, high recovery rates, and robust filtration.

10. Aseptic Filling Solution Enhances Sterility Assurance for Pharma Manufacturer 11/21/2024

    Emergent BioSolutions upgraded its Winnipeg site with the Cytiva SA25 aseptic filling workcell to improve sterility assurance, product flexibility, and regulatory compliance for CGT manufacturing.