Newsletter | February 17, 2026

02.17.26 -- Avoiding Protein Purification Artifacts That Still Undermine Drug Design

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Bioprocessing is evolving fast, are you keeping up?

Join Proteins, Antibodies & ADCs 2026, part of NextGen Biomed for practical strategies on designing, optimizing, and scaling biologics. Hear Charlotte Deane on AI in protein design, plus real-world case studies across upstream, downstream, and manufacturing. Then unwind at Comedy Night with Simon Brodkin. London | 24–25 March 2026 | Join us.

FEATURED EDITORIAL

Avoiding Protein Purification Artifacts That Still Undermine Drug Design

Protein purification artifacts are common technical issues, but when they go unnoticed, they can distort structural data and later lead to unreliable experimental results.

The Next Frontier In Drug Discovery: Reinventing Old Platforms To Solve New Problems

By combining proven technologies with new biological targets, we can create therapies that retain known safety while addressing emerging or previously intractable diseases.

INDUSTRY INSIGHTS

Innovative Technology For Developing, Scaling Peptide-Based Therapeutics

Watch as experts walk through several technologies and case studies, focusing on liquid-phase peptide synthesis, crystallization, method development for impurity analysis, and more.

Mirror, Mirror Makes RNA-targeted Discovery Smarter

Examine a mirror‑image screening approach that eliminates DNA:RNA hybridization, revealing true binders and unlocking clearer, more productive DEL results for challenging RNA targets.

Discovery Studies: The Foundation Of Drug Development Success

Combining rigorous target validation, early toxicity and pharmacokinetic (PK) testing, and an iterative design process is crucial for identifying viable drug candidates early.

Designing Shelf-Stable, Dry Powder Vaccines To Improve Global Access

Spray dry technology is being leveraged to create shelf-stable, dry-powder vaccines to treat and prevent the spread of tuberculosis which could significantly improve our global response to disease.

Detect Ultra-Rare Variants In cfDNA From Liquid Biopsy Samples

Liquid biopsy, powered by next-generation sequencing, is transforming precision oncology to offer real-time, non-invasive insights into tumor genetics, which revolutionizes how we monitor cancer.

Innovative AI-Driven Solutions To Address The Growing Complexity Of APIs

Computer-aided synthesis planning (CASP) can mitigate the impact of rising complexity. Here, we discuss the award-winning AI and vast data that propel a leading predictive retrosynthesis technology.

A Human-Relevant Model Of The Liver Sinusoid

This organ-on-a-chip model minimizes drug absorption while maintaining the essential architecture. Explore the specifications of this product engineered to model the human liver.

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Lab Equipment And Testing Site Matrix

Our Small Molecule Development And Manufacturing Experience

Productive Pipetting From 1 To 384 Channels