FEATURED EDITORIAL
"Should we build out an internal group of scientific expertise or delegate work to external vendors?," is a question that this author has faced in his career. He shares key considerations building protein science teams.
- The 2 Factors Driving A Surge In Aptamer Use In Drug Discovery
- FDA Adopts ICH Guidance On Assessing Nonclinical Biodistribution Of Gene Therapy Viral Vectors
- Optimizing Digitalization To Accelerate Your R&D
- Leveraging AI In Drug Discovery To Treat MS & Other Autoimmune Diseases
- Key Considerations For Developing Next-Generation Antibody-Drug Conjugates
- India’s CROs & CDMOs Come Of Age In The Global Marketplace
- 5 Characteristics Of The Automated Microbiology Lab Of The Future
FEATURED APPLICATION CONTENT
-
In this study, we used mechanistic modeling to investigate how AAV-resin interactions are affected when MgCl2 is used as an elution additive.
-
A step-by-step high-throughput process development (HTPD) workflow to determine the optimal resin and initial conditions for hydrophobic interaction chromatography (HIC).
-
In this study, we looked at how different antibody binding sites of a protein A ligand are affected by cleaning in place (CIP).
-
Discover a novel approach for manufacturing chemically defined media with precision control of trace impurities that utilizes innovative raw material analysis, data analytics, and a proprietary algorithm.
-
This article discusses how a combination of optimizing your process development, and process intensification can help drive the cost of dose down.
-
Typically, devices containing depth media filters can offer more efficient filtration. Browse depth filtration products and devices for the downstream processing of cell culture solutions, fermentation broths, and lysates.
-
Treatments for glioblastoma multiforme (GBM) are in high demand. Learn more about the new possibilities for increased dosing and diffusion capabilities offered by nanoformed APIs.
-
A novel downstream processing system was developed to mitigate the downstream processing bottleneck in cell line development. Evaluate the performance of this innovative system in a mAb production process.
-
Antibody-drug conjugates (ADCs) represent a significant area of growth in the biopharmaceutical industry. Explore the capabilities of a highly scalable, productive platform to streamline ADC production processes.
-
The first line of defense against cold chain failures is the integrity of freezing containers during storage and shipping. Explore "robust by design" single-use solutions in cold chain management.
-
To evaluate mixing performances across new equipment and consumables to ensure consistency, CFD is invaluable in determining the performance of single-use mixers during process development.
-
Learn about the basic principles that govern tangential flow filtration (TFF) along with the use of TFF capsules and cassettes in laboratory and process development applications.
FEATURED NEWS HEADLINES
- REALM IDx Launches REALM Pharma Services To Improve Drug Development And Research
- AI Drug Discovery Will Power Collaboration With Pharos Therapeutics
- Analog Pharma And Dipharma Announce US FDA Approval Of Abbreviated New Drug Application (ANDA) Of 20mg Generic Nitisinone Capsules (Temperature Stable)
- MetrioPharm Receives Orphan Drug Designation For The Treatment Of Duchenne Muscular Dystrophy
- FAR Biotech And Aragen Life Sciences Enter Into A Collaboration To Advance Preclinical Program In Neurodegeneration
- Janssen Submits New Drug Application To U.S. FDA Seeking Approval Of Investigational Single Tablet Combination Therapy Of Macitentan And Tadalafil For Treatment Of Patients With Pulmonary Arterial Hypertension (PAH)
- Scientists Develop Probe That Could Unlock The Mysteries Of A Vital Cellular Messenger And Pave The Way For New Drug Discoveries
- XtalPi Announces Collaboration With Lilly, Using AI+ Robotics To Uncover First-In-Class Therapeutics
- AION Labs, In Continued Partnership With BioMed X, Launches New Global Call For Applications: Identification Of Active Small Molecules For Drug Discovery
- InSilicoTrials And IBSA Join Forces To Innovate Clinical Trials With Advanced Computer Modeling
ARCHIVED NEWSLETTER
- 05.30.23 -- Small Molecule Drug Discovery: Can AI Do It All?
- 05.26.23 -- Increasing Oral Bioavailability With Solid Form Options
- 05.24.23 -- Addressing Micronization Challenges While Improving Solubility And Sustainability
- 05.23.23 -- Demonstrating Control Over The Manufacturing Process: QbD Studies
- 05.16.23 -- Increase Drug Development Efficiency Using Nanotechnology