FEATURED APPLICATION CONTENT

• Chemoenzymatic N-glycan Conjugation Of Native mAbs Provides Homogeneous, Efficacious ADCs

  A chemoenzymatic two-stage protocol enables DAR2 ADCs from native, non-engineered mAbs via glycan remodeling at Asn-297 and copper-free click chemistry, with in vivo efficacy outperforming a comparable marketed ADC.

• Bringing Novel ADC Formats Into The Clinic: AOC Process Development

  Antibody-oligonucleotide conjugates introduce conjugation and purification challenges that standard ADC process development wasn't designed to solve. This white paper details practical approaches for each.

• Accelerating Cell Therapy Discovery With High-Throughput Electroporation

  Discover how high-throughput electroporation-based screening can compress your CAR-T optimization timeline while delivering reproducible, scale-ready results across multiple donor samples.

• Organ-On-A-Chip Technology Unlocks Patient-Derived Precision Medicine

  Personalized medicine struggles with models that fail to reflect real human biology. Organ-on-a-Chip systems recreate tissue complexity, helping predict patient-specific treatment responses.

• How Isogenic Organ-Chips Are Transforming The Future Of Research

  Modeling the human brain requires more than simplified systems. New approaches that incorporate diverse cell types are improving how researchers study neurovascular function with greater precision.

• Shining A Light On Dark Data

  Centralizing data unlocks faster insights, reduces duplicated effort, and improves compliance. By overcoming silos and “dark data,” organizations can enable efficient search, reuse, and analysis.

• Filling Gaps In Drug Discovery Pipelines: From Candidate To Clinic

  See how existing partnerships with NIH allowed the chance to bring together government, academic, and industry resources through strategic initiatives that streamline processes and maximize benefits.

• Mammalian Expression

  See how a biotechnology company advanced an engineered protein therapeutic while navigating development, regulatory, and scalability challenges. 

• Integrated Stability Workflows That Reduce Manual Data Handling

  Integrated accelerated stability workflows reduce manual data handling while improving confidence in shelf‑life predictions. Help your teams move faster with fewer experimental demands.

• Workflow For Chemical Characterization And Database Curation

  Confident identification of known and unknown compounds starts with smarter LC/MS and GC/MS workflows. Learn how structure elucidation, verification, and centralized data curation work together.

• Improving pKa Prediction Accuracy For PROTACs

  Gain insight into how localized modeling of ionizable centers, supported by curated experimental data, delivers reliable predictions that strengthen physicochemical decision-making.

• Property-Based Optimization Of Pharmaceutical Lead Compounds

  Property-driven optimization helps medicinal chemists focus synthetic effort where it matters most. See how integrating ADME and physicochemical predictions can surface better-balanced lead candidates.