FEATURED APPLICATION CONTENT

• Harnessing Targeted Protein Degradation

  A leading biotech company working in the targeted protein degradation space was looking for fast delivery of the compounds, open, transparent and on-time communication, and flexibility and ability to scale.

• Apheresis Variability Control In Cell Therapy Manufacturing

  Explore our best practices for apheresis collection and obtention of enriched product for cell therapies.

• Tuning Intermediate Volumes On Sepax™ C-Pro Cell Processing System

  Discover how we automate the optimizing cell harvesting process and further minimize the potential for cell loss during wash steps.

• Natural Killer Cells Manufacturing

  Follow the feasibility of xeno‑free NK cell expansion, closure of key unit operations, and how future work could focus on fine‑tuning each step to generate a robust, scalable process.

• Optimizing Recovery On The Sepax™ Cell Processing System

  Using a model T-cell line, we demonstrate the impact of varying rinse volume, intermediate volume, and manual extraction parameters on overall cell recovery with a final product dose volume of 20 mL.

• Systems Employ New Single-Pass TFF Technology To Simplify Processes And Lower Costs

  Single-pass TFF technology brings practical and economic advances to TFF by simplifying the process and creating new capabilities.

• Outstanding Sensitivity For Confident SPR Interaction Analysis

  Explore how surface plasmon resonance (SPR)-based analyses with a high sensitivity instrument can provide greater data precision and better confidence in your results interpretation.

• Explore Protein Interactions Beyond Affinity To Boost Your Academic Research

  Explore how you can simplify research on protein-protein interactions using our SPR systems.

• Guide For DNA Transfection For Gene Therapy Vector Manufacturing

  When considering the manufacturing of gene therapy vectors or recombinant vaccines, selection of the most appropriate technology is key. Here we review a powerful and flexible platform for DNA transfection.

• High Concentration Monoclonal Antibody Drugs Manufacturing Challenges

  A review of high-conentration mAb manufacturing challenges including viscosity, aggregation, instability, and the effect of excipients on formulation, filtration, and fill and finish and bioavailability.

• Performing Large Scale Targeted Peptide Quantification

  This study examines a QTOF system that can collect high-resolution, high mass accuracy, full-scan MS and MS/MS data.

• Simultaneous Spray Drying For Combination Dry Powder Inhaler Formulations

  Three combination case studies are demonstrated, in which bevacizumab is paired with erlotinib, cisplatin, or paclitaxel in a dry powder inhaler formulation.