FEATURED EDITORIAL
Ibogaine’s anecdotal and clinical signals on cravings, withdrawal, and PTSD are growing, but the biggest obstacle is that ibogaine carries serious cardiac risk and hallucinations.
- What I Heard When NAMs Became a Conversation, Not a Webinar
- Using Low-Intensity Focused Ultrasound To Open The Blood–Brain Barrier
- Wall Street Is Wary Of NAMs — And For Good Reason: The Evidentiary Shift
- Measuring Cellular Water Content As A New Tool For Organoid Characterization
- Engineering CAR T Cells With mRNA-LNPs: Applying Oncology Learnings To Allergic Diseases
- Moving Beyond The mRNA Momentum: The Preclinical Path To Personalized Scalable Solid Tumor Immunotherapies
- The Future Of Cancer Drug Discovery Is Targeted Immune Activation
FEATURED APPLICATION CONTENT
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SDD scale-up introduces scale-dependent risks that threaten bioavailability, stability, and manufacturability. This white paper details a model-based framework for managing those risks from early feasibility through commercial production.
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A chemoenzymatic two-stage protocol enables DAR2 ADCs from native, non-engineered mAbs via glycan remodeling at Asn-297 and copper-free click chemistry, with in vivo efficacy outperforming a comparable marketed ADC.
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Antibody-oligonucleotide conjugates introduce conjugation and purification challenges that standard ADC process development wasn't designed to solve. This white paper details practical approaches for each.
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Discover how high-throughput electroporation-based screening can compress your CAR-T optimization timeline while delivering reproducible, scale-ready results across multiple donor samples.
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Personalized medicine struggles with models that fail to reflect real human biology. Organ-on-a-Chip systems recreate tissue complexity, helping predict patient-specific treatment responses.
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Modeling the human brain requires more than simplified systems. New approaches that incorporate diverse cell types are improving how researchers study neurovascular function with greater precision.
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Centralizing data unlocks faster insights, reduces duplicated effort, and improves compliance. By overcoming silos and “dark data,” organizations can enable efficient search, reuse, and analysis.
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See how existing partnerships with NIH allowed the chance to bring together government, academic, and industry resources through strategic initiatives that streamline processes and maximize benefits.
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See how a biotechnology company advanced an engineered protein therapeutic while navigating development, regulatory, and scalability challenges.
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Integrated accelerated stability workflows reduce manual data handling while improving confidence in shelf‑life predictions. Help your teams move faster with fewer experimental demands.
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Confident identification of known and unknown compounds starts with smarter LC/MS and GC/MS workflows. Learn how structure elucidation, verification, and centralized data curation work together.
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Gain insight into how localized modeling of ionizable centers, supported by curated experimental data, delivers reliable predictions that strengthen physicochemical decision-making.
- What I Heard When NAMs Became a Conversation, Not a Webinar
- A Simple Eye Drop For A Blinding Disease? Claris Bio Raises $118M And Prepares For Pivotal Trials
- What The China Biotech Debate Reveals About U.S. Drug Discovery
- Why Ending Rh Disease Requires More Than A Breakthrough (Part 3 of 3)
- Chinese Competition And The Future Of Science: Insights From The U.S. Science Summit
DRUG DISCOVERY CONTENT COLLECTIONS
Drug discovery is moving beyond traditional hit identification toward data-driven strategies that extract deeper insight from large-scale screening datasets. Advances in DNA-encoded library (DEL) screening, computational tools, and machine learning are helping teams make more informed decisions in early-stage drug development. Access this brand-new Drug Discovery Online content collection for an under-the-hood look at modern approaches to turning large discovery datasets into actionable insight.
FEATURED NEWS HEADLINES
- Emulate Enters Final Stage Of FDA ISTAND Program For Human Liver-Chip With Submission Of Qualification Package Covering Both Zoë® And AVA™ Organ-Chip Platforms
- Twist Bioscience Joins Lilly Tunelab To Advance Antibody Drug Discovery
- Novo And Anthropic Will Collaborate To Advance Drug Discovery With Claude
- IASO Bio's CD20-Targeted In Vivo CAR-T Therapy IASO208 Receives FDA IND Clearance
- GATC Health Joins Critical Path Institute's New Approach Methodologies Developer Coalition To Advance AI-Enabled Regulatory Science
- FDA Approves Telix's Brain Cancer Imaging Drug Pixclara
- Sapience Therapeutics Announces FDA Acceptance Of Investigational New Drug Application For ST316 In Familial Adenomatous Polyposis (FAP)
- Accro Bioscience Announces Inclusion Of AC-101 Tablets In The NMPA CDE's 'Caring Plan-Extension' Pilot Program For Rare Disease Drug Development
- EPIK Biosciences Advances Combination Medicines Across Ketamine-Based And DXM-Based Programs, Supported By 34 Provisional Drug Patent Applications
- Lonza Further Strengthens US Manufacturing Presence With Addition Of A Commercial Spray-Drying Facility In Bend, Oregon
ARCHIVED NEWSLETTER
- 09.16.26 -- Smarter Ways To Reduce Risk, Downtime, And Lifecycle Surprises
- 09.15.26 -- A Simple Eye Drop For A Blinding Disease? Claris Bio Raises $118M And Prepares For Pivotal Trials
- 09.10.26 -- Advance Drug Development With Analytical Characterization Solutions
- 09.08.26 -- Which Discovery Technologies Help Solve Degrader Assay Gaps
- 09.05.26 -- Drug Discovery Online Best Of August
