Although change may be intimidating, disruptive innovation allows manufacturers to achieve increased efficiency and quality. Several drivers affect how the appropriate facility design and unit operations for a process are selected, making it imperative to properly evaluate each option.
This study presents how strategic enhancements to the sparge and agitation systems of Thermo Scientific™ HyPerforma™ S.U.B.s have revealed the potential for a three- to four-fold improvement in mixing and mass transfer performance compared to legacy S.U.B. designs.
The HyPerforma S.U.F. performs similarly to stainless steel SIP/CIP fermentors, making it the best option against other single-use reactors that fall below the mark.
A collaborative study with a new customer with the objective of taking an existing, smaller preclinical E. coli process previously performed in stainless steel vessels and scaling it up quickly using the Thermo Scientific™ HyPerforma™ 300 L Single-Use Fermentor (S.U.F.)
A leading multinational pharmaceutical company approached Fisher Clinical Services with an extensive clinical trial pipeline and the need to achieve a comprehensive, fully-managed transportation strategy. Learn more about our outsourced transportation option that delivered tangible results.
Given the rapidly changing landscape of today's trials, if sponsors wish to succeed, they must remain vigilant - attending to every detail of the process. Learn more about how several sponsors achieved success through these case-study examples.
Understanding the challenges in the biopharma space is critical, as the planning you do today dictates the options you have later when the costs — and the stakes — get even higher.
How far have we come in raw material supply management, and what still needs accomplished to ensure the delivery of safe and effective drugs?
The performance of two assays for determination of adenovirus concentration based on surface plasmon resonance (SPR) is demonstrated in this application note.
Here, we describe the development of two effective downstream processes for purification of adenovirus from cell culture harvest.