FEATURED EDITORIAL
Intratumoral injection bypasses the tumor’s physical defenses entirely, killing cancer cells and creating a personalized immune response that destroys solid tumors.
- Video Spotlight: Harvard's Alice Stanton On Engineering Integrated Human-Derived miBrain Organoid Models
- Elusive Success Of CDK2: Why That May Be Changing
- Microneedle Delivery Of Telomerase Protects Skin From Radiation-Induced DNA Damage
- Structural Biology Wages War On HIV And The Pandemics Of Tomorrow
- The Matchmaker Modality: Engineering Event-Driven Pharmacology With Induced Proximity
- A State Of Stress: Developing Therapeutics Rooted In Cell Behavior
- Beyond KRAS G12C: New Approaches For Drugging The Undruggable
FEATURED APPLICATION CONTENT
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Explore how leveraging expert CDMO partnerships can streamline the development process and enhance the efficacy of your bispecific antibody therapies.
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Consider this alternative immunization approach — the PentaMice platform, a collection of five wildtype mouse strains bred in-house for increased MHC class II diversity — and how we're leveraging it for COVID-19 antibody discovery.
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By forging strategic partnerships with comprehensive CDMOs, see how emerging biopharma firms can navigate through early-phase development and ensure a smooth transition to clinical advancement.
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Explore how advanced single‑cell analysis links CAR localization, cell structure, and functional behavior, offering deeper insight into CAR T cell heterogeneity and performance.
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Gain insight into automating DNA size selection that shows how optimized bead ratios and programmable handling improve fragment recovery, consistency, and throughput.
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Gain insight into an automated high‑input workflow that streamlines long‑read whole‑genome library prep, supporting large DNA fragments while reducing reagent use.
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A streamlined workflow reduces reagent use and hands‑on time while preserving long‑read sequencing quality. See how multiplexed offer an efficient option for scaling or mobilizing sequencing efforts.
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Understanding covalent warhead kinetics is key to reducing safety risks early in discovery. Learn about a new approach to GSH‑based measurements that offers clearer predictors of toxicity.
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See how a rapid digital PCR workflow enables reliable detection of trace RCL levels while maintaining strong performance in complex samples, which support more confident decisions in manufacturing.
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Discover how mixed-mode chromatography enables high-yield purification of single-domain antibodies under mild conditions and why these approaches outperform traditional resins.
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Scalable lentiviral vector production is moving beyond adherent systems. Learn how streamlined workflows enable linear scale-up in stirred-tank bioreactors for cost-effective gene therapy manufacturing.
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Decoding immune cell interactions reveals critical insights for cancer therapy. Advanced imaging and spectral analysis enable precise identification of synapses, accelerating immuno-oncology research.
- Video Spotlight: Harvard's Alice Stanton On Engineering Integrated Human-Derived miBrain Organoid Models
- Insights From The Non-Opioid Pain Therapeutics Summit: Human-Centric Translational Models And The Reawakening Of Pain Pipelines
- Schrödinger's Equation Turns 100: How Quantum Chemistry Is Improving Drug Discovery
- Annual Reflections And Predictions From The Editors' Roundtable
- The Unlikely Weapon Against Fentanyl: Your Immune System
FEATURED NEWS HEADLINES
- Frontage Laboratories Completes Acquisition Of Teddy Lab, Strengthening Global Central Laboratory Capabilities
- iLoF And Industry Leader Bluepharma Announce Strategic Collaboration To Deploy AI-Powered Optomics® For Faster Drug Development And To Advance The Future Of Personalised Medicine
- Ensorcell Appoints Biopharma Industry Veterans Geoff Hodge And Amy Teachout To Senior Leadership Team
- BioDuro And Cenra Launch Joint Venture To Expand Resilient Global API Manufacturing Capacity
- Chemically 'Stapled' Peptides Used To Target Difficult-To-Treat Cancers
- Priovant Announces FDA Acceptance And Priority Review Of New Drug Application For Brepocitinib In Dermatomyositis
- Insilico Medicine And Liquid AI Announce Strategic Partnership Delivering Lightweight Scientific Foundation Models For Drug Discovery
- Gyre Therapeutics Enters Into Agreement To Acquire Cullgen To Gain Targeted Protein Degradation Platform And Pipeline
- Sanofi's Rilzabrutinib Earns Orphan Drug Designation In Japan For IgG4-Related Disease
- Ono Pharma Announces New Drug Discovery Collaboration With Congruence Therapeutics In The Priority Areas Of Neurology And Immunology
ARCHIVED NEWSLETTER
- 03.03.26 -- In Vivo LNP-Engineered Cytokine-Armored CAR Cells For Solid Tumors
- 02.24.26 -- Small Molecule Enzyme Mimetics In Age-Related Neurodegeneration
- 02.17.26 -- Avoiding Protein Purification Artifacts That Still Undermine Drug Design
- 02.10.26 -- Designing Drugs For Women: Closing The Therapeutic Gap
- 02.03.26 -- CROs In Early Drug Discovery, Part 3: Budgets, Timelines, And Avoiding Pitfalls