• Investigating The Important Parameters For Packing Nuvia HR-S Resin At Process Scale

    Process-scale production typically involves more than one column. The packing quality of each column affects the efficiency of the whole workflow and is an important validation criterion. Here, we investigate the effects of packing methods, packing solutions, compression factor, resin slurry concentration, and bed height on the efficiency of packed columns.

  • CAR-T Cell Lentiviral Transduction By Spinoculation

    There is a growing need to close and automate manufacturing of chimeric antigen receptor (CAR)-T cell therapies. CAR-T workflows depend on ex vivo gene transfer by lentiviral transduction for therapeutic efficacy. To streamline this step while keeping flexibility during process development, we introduced stand-alone SpinOculation C-Pro protocol software.

  • Robust Business Continuity Program Helps To Maintain Operations In The Face Of Crisis

    Experts at Cytiva provide insights into implementing a robust business continuity management program that can help secure supply, reduce risks, and maintain quality in manufacturing operations, through a crisis situation.

  • Telltale Signs You’re With The Wrong CDMO

    Is your CDMO an asset or a hindrance? This article explores 10 red flags that signal your parter isn't carrying its weight on your journey to commercialization.

  • How Buffer pH And NaCl Affect Size Exclusion Chromatography

    Using a design of experiments approach, this study describes the effect of buffer pH and NaCl concentration on proteins purified by size exclusion chromatography.

  • Automated High Throughput mAb Purification Using Fibro Technology

    Biomanufacturing is trending towards higher numbers of monoclonal antibody (mAb) projects and smaller batch sizes, with production of most mAbs below 100 kg/yr. These trends are fueling demands to screen more clones faster and improve the efficiency of process development (PD). Read how the Fibro PrismA unit provides a time advantage with comparable recovery and product quality attributes to resin-based column.

  • Refocusing R&D to Address Patient Care Needs During COVID-19 Uncertainty

    Refocusing R&D strategies towards diagnostics and considering industry partnerships should be key considerations when developing enterprise risk plans during a crisis like COVID-19. 

  • Robust Field Guide To qPCR

    qPCR remains the gold standard for validation of microarray and next generation sequencing data and the method of choice for both clinical and basic research labs for a wide range of applications. However, there remains general concern about the production of data that truly reflects the tested experimental conditions. We have developed a comprehensive guide to performing the ultimate qPCR experiment. The following is a snapshot of the critical steps needed to achieve excellent results.

  • Codetection Of Viral Pathogen RNA And DNA Using One-Step Multiplex RT-qPCR

    RT-qPCR is a well-established method for the detection, quantification, and typing of different microbial agents in the areas of clinical and veterinary diagnostics, as well as food safety. There are multiple benefits of this technology. In this application note, we demonstrate a sensitive codetection of viral RNA and DNA targets in a multiplex setting using a novel one-step multiplex RT-qPCR supermix.

  • Protein Thermal Shift Assays Made Easy

    Protein thermal shift assays enable quick and easy buffer optimization for increased protein stability. Learn more about the CFX Real-Time PCR Detection Systems which uses a simple protocol to measure protein thermal stability using SYPRO Orange Fluorescent Dye.

FEATURED PRODUCTS AND SERVICES

The ZE5 Cell Analyzer is an innovative new flow cytometer with flexible configurations to meet a broad range of experimental complexities and throughput needs. Whether it’s a low-complexity, or a high-complexity experiment, the ZE5 Analyzer has up to 30 parameters and provides a truly expandable flow cytometer. This flexibility makes the ZE5 Analyzer accessible for novice flow cytometry users yet flexible enough for the most experienced flow cytometry professionals

Gibco BioProduction Services can support and partner with you no matter what your comfort level is with intellectual property.  Our team of professionals will work with you to provide the best customized solution for your particular situation.  You will receive exceptional customer service from start to finish.

Data-driven risk assessment enables smart decisions on development strategy.

For over 15 years, GVK BIO has been supporting the chemistry needs of clients in the Pharma, Agrochem and material science space. These services are either provided as “Fee for Service” or “FTE” model. We cater to requirement of clients by providing them Medchem support, Library generation or simple plain Syntheses. Apart from designing small molecules and libraries, highly challenging syntheses and isolation of natural products, steroids, carbohydrates, peptides, macro cycles and nucleosides, is accomplished on a routine basis. The prime objective of our team is to accelerate research and development of our clients by providing them valuable scientific solutions with speed and quality.

The Model 910 Gas Chromatograph performs routine and complicated applications generating accurate and reproducible results...

This XDR single-use bioreactor is sized for the benchtop, yet allows smooth scale-up to full production.

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