FEATURED EDITORIAL
We caught up with Davinder Ramsingh, MD, to talk about the potential of using low-intensity focused ultrasound (LIFU) to open the blood–brain barrier.
- Engineering CAR T Cells With mRNA-LNPs: Applying Oncology Learnings To Allergic Diseases
- Moving Beyond The mRNA Momentum: The Preclinical Path To Personalized Scalable Solid Tumor Immunotherapies
- The Future Of Cancer Drug Discovery Is Targeted Immune Activation
- Will 2027 See A Meteoric Rise Of Programmable Nanomedicine?
- A Simple Eye Drop For A Blinding Disease? Claris Bio Raises $118M And Prepares For Pivotal Trials
- Emerging Fields In Immunology: New Frontiers For Therapeutic Discovery
- Turning Pediatric Cancer Discoveries Into Medicines Requires Better Connections
FEATURED APPLICATION CONTENT
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SDD scale-up introduces scale-dependent risks that threaten bioavailability, stability, and manufacturability. This white paper details a model-based framework for managing those risks from early feasibility through commercial production.
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A chemoenzymatic two-stage protocol enables DAR2 ADCs from native, non-engineered mAbs via glycan remodeling at Asn-297 and copper-free click chemistry, with in vivo efficacy outperforming a comparable marketed ADC.
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Antibody-oligonucleotide conjugates introduce conjugation and purification challenges that standard ADC process development wasn't designed to solve. This white paper details practical approaches for each.
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Discover how high-throughput electroporation-based screening can compress your CAR-T optimization timeline while delivering reproducible, scale-ready results across multiple donor samples.
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Personalized medicine struggles with models that fail to reflect real human biology. Organ-on-a-Chip systems recreate tissue complexity, helping predict patient-specific treatment responses.
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Modeling the human brain requires more than simplified systems. New approaches that incorporate diverse cell types are improving how researchers study neurovascular function with greater precision.
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Centralizing data unlocks faster insights, reduces duplicated effort, and improves compliance. By overcoming silos and “dark data,” organizations can enable efficient search, reuse, and analysis.
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See how existing partnerships with NIH allowed the chance to bring together government, academic, and industry resources through strategic initiatives that streamline processes and maximize benefits.
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See how a biotechnology company advanced an engineered protein therapeutic while navigating development, regulatory, and scalability challenges.
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Integrated accelerated stability workflows reduce manual data handling while improving confidence in shelf‑life predictions. Help your teams move faster with fewer experimental demands.
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Confident identification of known and unknown compounds starts with smarter LC/MS and GC/MS workflows. Learn how structure elucidation, verification, and centralized data curation work together.
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Gain insight into how localized modeling of ionizable centers, supported by curated experimental data, delivers reliable predictions that strengthen physicochemical decision-making.
- A Simple Eye Drop For A Blinding Disease? Claris Bio Raises $118M And Prepares For Pivotal Trials
- What The China Biotech Debate Reveals About U.S. Drug Discovery
- Why Ending Rh Disease Requires More Than A Breakthrough (Part 3 of 3)
- Chinese Competition And The Future Of Science: Insights From The U.S. Science Summit
- Rhogam's Unconventional History And Why There Is No True Synthetic Replacement (Part 2 of 3)
DRUG DISCOVERY CONTENT COLLECTIONS
Drug discovery is moving beyond traditional hit identification toward data-driven strategies that extract deeper insight from large-scale screening datasets. Advances in DNA-encoded library (DEL) screening, computational tools, and machine learning are helping teams make more informed decisions in early-stage drug development. Access this brand-new Drug Discovery Online content collection for an under-the-hood look at modern approaches to turning large discovery datasets into actionable insight.
FEATURED NEWS HEADLINES
- Creative Biolabs Expands Integrated AI-Driven Chemical Synthesis Platforms To Accelerate Next-Generation Drug Discovery
- Satellos Announces Forazapadin As Assigned International Nonproprietary Name For Lead Drug Candidate, SAT-3247
- Revvity To Acquire Human Cell Design To Advance Human-Relevant Cell Models For Metabolic Disease Drug Discovery
- Alebund Pharmaceuticals Announces FDA Clearance Of IND Application For AP308 For The Treatment Of IgA Nephropathy
- Nature Biotechnology | Insilico's AI-Driven IPF Candidate Rentosertib Shows Potential For Biological Age Reversal, As Assessed By Six Proteomic Aging Clocks
- Acepodia Announces FDA Clearance Of IND Application For ACE723, A Novel Dual-Payload Antibody-Drug Conjugate
- Lupin Receives U.S. FDA Approval For Modafinil Tablets, USP
- Kali Therapeutics Receives U.S. FDA Clearance For KT501 Investigational New Drug Application
- Nuffield Department Of Medicine At The University Of Oxford And 2U Launch New Program In AI-Driven Drug Discovery
- Tigermed And Veeda Lifesciences Forge Strategic Clinical Research For Global Drug Development
ARCHIVED NEWSLETTER
- 09.10.26 -- Advance Drug Development With Analytical Characterization Solutions
- 09.08.26 -- Which Discovery Technologies Help Solve Degrader Assay Gaps
- 09.05.26 -- Drug Discovery Online Best Of August
- 09.03.26 -- How Imaging And Translational Models Solutions Are Accelerating Discovery
- 09.01.26 -- Shelf Stable Bioprinted Human Tissue Models: A 2026 Nucleate Boston Activator Cohort Interview With Carlos Ezio, CEO, Criocore
