• The Commercial Manufacturing Journey: Strategies For A Successful Launch
    The Commercial Manufacturing Journey: Strategies For A Successful Launch

    Four Catalent Biologics experts share how scale-up, regulatory expectations, demand forecasting and process validation play into the success of a biologic's commercial manufacturing journey.

  • Standardizing Process Characterization And Late Phase Development
    Standardizing Process Characterization And Late Phase Development

    Process characterization is an important step in the overall journey of product development. This case study proposes an approach for process characterization for the production of a monoclonal antibody, specifically at the drug substance biomanufacturing step.

  • Lentiviral Vector Scale-Up Workflow In Single-Use Bioreactors Enables GMP Compliance
    Lentiviral Vector Scale-Up Workflow In Single-Use Bioreactors Enables GMP Compliance

    As gene transfer vehicles, lentiviruses exhibit many desirable properties, such as high transduction efficiencies, ability to infect both dividing and nondividing cells, and stable integration into the host cell genome. These properties make them well-suited for in vivo and ex vivo gene and cell therapies. However, cost-effective manufacturing of lentiviral vectors (LV) at commercial scales has proven difficult and remains a pressing issue for the marketing of therapies that depend on their application.

  • Flow Chemistry vs. Batch Processes
    Flow Chemistry vs. Batch Processes

    Traditionally, new chemicals are developed using batch processing, which fully relies on versatile and qualified equipment to perform different unit operations. To address these challenges, continuous flow chemistry technology is emerging as an effective tool to conduct chemical synthesis.

  • Unexpected SEC Results – Can It Be Improved?
    Unexpected SEC Results – Can It Be Improved?

    Sometimes your size exclusion chromatography (SEC) results don’t look like you want them to. Fix issues like poor resolution, peak tailing and fronting with the tips in this FAQ.

  • Master Analytical SEC Running Conditions
    Master Analytical SEC Running Conditions

    Need to find out how to calibrate your size exclusion chromatography (SEC) column? Or how different additives affect your results? Read these useful insights.

  • Quality Matters – SEC Analysis For Antibody Aggregates
    Quality Matters – SEC Analysis For Antibody Aggregates

    Size exclusion chromatography (SEC) is the go-to analytical method in the analysis of therapeutic protein drugs. This article describes the factors affecting the reproducibility of columns and how you can minimize column variation.

  • Developability Assessment Of Small Molecules
    Developability Assessment Of Small Molecules

    Developability assessment or preformulation studies of small molecule is an important part the of drug discovery process leading to selection of New Chemical Entities (NCEs) for clinical studies. This white paper dives deeper into why we need developability assessment as well as its processes.

  • Expanded Droplet Digital PCR Multiplexing Capability Using Two Different Strategies
    Expanded Droplet Digital PCR Multiplexing Capability Using Two Different Strategies

    Droplet Digital PCR (ddPCR) enables easy multiplexing of numerous targets within each fluorescent channel. Amplitude-based multiplexing achieves this by varying primer and/or probe concentrations. In probe-mixing multiplexing, probes are mixed at desired concentrations to place targets in a defined position on a 2-D plot. This paper describes strategies for both approaches using the large portfolio of ddPCR Assays readily available through Bio‑Rad.

  • EDGE Confocal Imaging Technology
    EDGE Confocal Imaging Technology

    Increasingly, scientists are being challenged to study more biologically-relevant model systems, and this often means imaging thick, demanding 3D samples that may also be alive. Read how IRIS and EDGE confocal imaging can offer high contrast imaging of thicker samples.

FEATURED PRODUCTS AND SERVICES

ZE5™ Cell Analyzer ZE5™ Cell Analyzer

The ZE5 Cell Analyzer is an innovative new flow cytometer with flexible configurations to meet a broad range of experimental complexities and throughput needs. Whether it’s a low-complexity, or a high-complexity experiment, the ZE5 Analyzer has up to 30 parameters and provides a truly expandable flow cytometer. This flexibility makes the ZE5 Analyzer accessible for novice flow cytometry users yet flexible enough for the most experienced flow cytometry professionals

An Overview of BIOVIA Environmental Health and Safety Solutions An Overview of BIOVIA Environmental Health and Safety Solutions

Organizations need to manage chemicals safely from receipt to disposal along the entire lab-to-plant value chain, ensuring Environmental Health and Safety (EH&S) compliance across the enterprise.

Arcos™ Block Management System Arcos™ Block Management System

Minimize errors, increase productivity and keep your laboratory’s resources focused on what matters most—positive patient outcomes—with the Thermo Scientific™ Arcos™ Block Management System.

Single-Use, Flexible Stirred-Tank Bioreactor System: Xcellerex XDR-10 Single-Use, Flexible Stirred-Tank Bioreactor System: Xcellerex XDR-10

This XDR single-use bioreactor is sized for the benchtop, yet allows smooth scale-up to full production.

Chemistry CRO Services Chemistry CRO Services

For over 15 years, GVK BIO has been supporting the chemistry needs of clients in the Pharma, Agrochem and material science space. These services are either provided as “Fee for Service” or “FTE” model. We cater to requirement of clients by providing them Medchem support, Library generation or simple plain Syntheses. Apart from designing small molecules and libraries, highly challenging syntheses and isolation of natural products, steroids, carbohydrates, peptides, macro cycles and nucleosides, is accomplished on a routine basis. The prime objective of our team is to accelerate research and development of our clients by providing them valuable scientific solutions with speed and quality.

Gibco BioProduction Services Gibco BioProduction Services

Gibco BioProduction Services can support and partner with you no matter what your comfort level is with intellectual property.  Our team of professionals will work with you to provide the best customized solution for your particular situation.  You will receive exceptional customer service from start to finish.

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INDUSTRY EVENTS

Essentials of Disinfectant Efficacy Testing – Ensuring Microbial Control December 12 - 12, 2019
1pm-2:30pm EST, Online Training
Effective Batch Record Review – Getting It Right The First Time January 8 - 8, 2020
1:00pm - 2:30pm EST, Online Training
Clinical Research Project Management - 7 Breakthrough Behaviors For Success January 14 - 14, 2020
1pm-2:30pm EDT, Online Training
Understanding Aseptic Technique and Cleanroom Behavior – Avoiding Human Error January 15 - 15, 2020
1pm-2:30pm EST, Online Training
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 UPCOMING TRAINING COURSES

Essentials of Disinfectant Efficacy Testing – Ensuring Microbial Control December 12 - 12, 2019
1pm-2:30pm EST, Online Training
Effective Batch Record Review – Getting It Right The First Time January 8 - 8, 2020
1:00pm - 2:30pm EST, Online Training
Clinical Research Project Management - 7 Breakthrough Behaviors For Success January 14 - 14, 2020
1pm-2:30pm EDT, Online Training
Understanding Aseptic Technique and Cleanroom Behavior – Avoiding Human Error January 15 - 15, 2020
1pm-2:30pm EST, Online Training
More Upcoming Courses