Newsletter | March 3, 2026

03.03.26 -- In Vivo LNP-Engineered Cytokine-Armored CAR Cells For Solid Tumors

SPONSOR

Join this live discussion designed for scientists and leaders seeking to understand where open-source AI is delivering real impact today—and why AI is no longer optional for staying competitive in drug discovery. Registration is free, more info here.

FEATURED EDITORIAL

In Vivo LNP-Engineered Cytokine-Armored CAR Cells For Solid Tumors

By Parv Barot

By injecting lipid-based nanoparticles encapsulating mRNA and encoding the CAR directly into the bloodstream, developers can effectively reprogram the patient's own immune cells in situ.

Harnessing Mitochondria: A New Frontier In Therapeutic Innovation

By Natalie Yivgi-Ohana, Minovia Therapeutics

What if we can replace damaged mitochondria with young and healthy mitochondria? In recent years, a new therapeutic field has evolved: mitochondrial transplantations.

INDUSTRY INSIGHTS

How GMP And Clinical Rules Shape Upstream Discovery And Development

Video | BD Biosciences

Early collaboration between R&D and manufacturing ensures regulatory readiness and efficiency. Learn how automation and robust panel design enable clinical translation for advanced cell therapy.

Advanced Analytical Tools To De-Risk Pharmaceutical Development

E-Book | Lonza

Discover three tools that facilitate a successful journey from candidate compound to clinical triumph: solid form screening, PBPK modeling, and AI-enabled route scouting.

De-Risking Early Phase Micronization With Integrated Solid Form Selection

Webinar | Lonza

Review the crucial selection of the optimal solid form in  carefully achieving successful jet milling of APIs designed specifically for pulmonary administration through the pulmonary route.

Fast Track RNA-LNP Drug Development By Lowering The Lipid Barrier

Article | Cytiva

Fast-track RNA-LNP development, streamline screening with off-the-shelf ionizable lipid mixes, and utilize validation strategies to generate reproducible and scalable LNPs for lead candidates.

Unlock The 3 Keys To Drug Discovery Success

Article | Labcorp Drug Discovery Solutions

If you don’t know where you are going, how will you get there? Articulating the destination of your therapeutic is essential for determining whether it is commercially viable and meets required milestones.

SOLUTIONS

Improve Precision With Low-Drug Absorption

Emulate

Digital PCR Analytics For Cell And Gene Therapy Workflows

QIAGEN