Analyze And Sort Cell-Cell Interactions In Real-Time Using Spectral Flow Cytometry To Accelerate Drug Discovery In Immuno-Oncology

Understanding immune cell communication is critical for advancing immunotherapy. Specialized junctions called immunological synapses dictate how T cells attack tumors, how macrophages respond, and how cancer evades immune defense. Traditional flow cytometry often discards these interactions as artifacts, limiting discovery. By integrating spectral flow cytometry with real-time imaging, researchers can now confidently identify and sort synaptic events, distinguish true biological interactions from coincident cells, and even detect overlapping synapses. Label-free imaging adds flexibility when fluorescence markers are reserved for other targets. This approach accelerates drug and biomarker development in immuno-oncology, offering unprecedented insight into cellular dynamics.

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