Drug Discovery Featured Articles & Applications

  1. 9 Trends That Will Carry Genomics Into 2020 (And Beyond)

    Remarkable advances in genomics technologies bring the promise of extraordinary changes in healthcare — and some of those changes are arriving now. What’s unfolding are nine trends that we think will shape the life science markets in this accelerating genomics revolution. First, some background on how we got here.

  2. 5 ADC Manufacturing Challenges You Need To Know

    Despite this tremendous growth, drug makers still face a number of challenges in the manufacturing process for ADCs. This article discusses five key areas where pharmaceutical manufacturers may face the biggest uphill battles.

  3. 10 Critical Components Of A Successful Global Drug Development Plan

    We use plans every day to help us arrive at our desired destinations.  Pilots utilize flight plans prior to take off — although they have flown to their destination perhaps hundreds of times before, they nevertheless reviews and follows a flight plan. Likewise, ship’s captains also file plans and chart courses. Road maps provide guidance on how to drive from point A to point B, though today most people rely on electronic global positioning systems (GPS) to assist with navigation.

  4. Opioid Crisis Pushing Changes To U.S. Chronic Pain Drug Market

    With the U.S opioid analgesic addiction and overdose crisis showing no signs of relenting, change is coming fast for manufacturers of chronic pain drugs.

  5. From Discovery To Development: GS Expression System For Next-Generation Biologics

    Compared to traditional antibody expression, where routine purification and analytical strategies have been established over the last few years, next-generation biologics have complex designs. If you are first in class or you have a very bespoke up- and downstream process, it also means you will have bigger hurdles to overcome when it comes to regulatory support and filing. At Lonza, these challenges are addressed with the GS™ expression platform.

  6. Digging Into The Details: Commonly Asked Questions About Lonza’s XS And GS Expression Systems

    No single strain or vector is capable of being the best expression option for all types of biopharmaceuticals. Experts from Lonza answers questions about the proprietary expression platforms the company has assembled to rapidly generate high-producing cell lines for biological candidates.

  7. Speed Up The Pace Of Chemical Research And Development

    Today’s chemical development labs are busy places that create fascinating new chemicals, new formulations and new products that boost the bottom line. But are these labs as efficient as they could be?

  8. Is Automation The Disruption Pharma R&D Needs?

    According to a recent report from PhRMA, U.S. biopharmaceutical companies spend more than 13 times the amount of R&D per employee than all other manufacturing industries.

  9. Improving Green Chemistry With An Electronic Lab Notebook
    The drive toward sustainable, “green” processes in biopharmaceuticals seems like a daunting challenge. However, the right tools can integrate “green” practices into every aspect of the development workflow. This case study explores how one BIOVIA customer rolled out BIOVIA Workbook across its process chemistry division to around 1,000 scientists and the “green” benefits the group saw.
  10. How Pacira Pharma Is Working To Help Curb The Opioid Epidemic

    The most effective way to stop opioid dependence is to eliminate the use of these addictive drugs after surgery altogether. This was the goal of Pacira Pharmaceuticals.