Drug Discovery Featured Articles & Applications

  1. Exploring Sanofi R&D's Batch Monitoring Initiative 10/23/2024

    The project established predictability during testing and release for the production of medicine to support clinical trials.

  2. Panavance Details IND Prep Ahead Of FDA Submission For Ovarian Cancer Trial 10/23/2024

    Panavance CEO Greg Bosch discusses the company’s pursuit of a second trial for misetionamide, walking us through IND preparations, CRO selection, and securing funding. 

  3. iPSC-based Gene Therapy: Applications And Challenges 10/15/2024

    Induced pluripotent stem cells (iPSCs) are generated by reprogramming adult somatic cells into a pluripotent state, meaning they can develop into any cell type in the human body. This has tremendous potential in regenerative medicine and gene therapy.

  4. Restoring Immune Homeostasis As A Development Approach To Treat And Modify Inflammatory Disease 10/8/2024

    Drawing from experiences with ongoing work at AnaptysBio, Inc., senior VP of research Martin Dahl, Ph.D., shares three considerations when developing immune cell modulators to treat and modify inflammatory disease.

  5. Keys To Successful CMC Source Document Preparation For Cell & Gene Therapies 10/1/2024

    Chemistry, manufacturing, and controls (CMC) source documents are the foundation for module 3 of a cell/gene therapy FDA regulatory submission.

  6. Tracking The Latest Developments In CAR T Safety And Efficacy 9/27/2024

    Here are some updates on the industry's quest to enhance CAR T cells' ability to target and destroy cancer while reducing adverse effects.

  7. Araris Doubles Down With Dual-payload ADC 9/24/2024

    Antibody-drug conjugates usually deliver one payload type, which can overlook cancer’s complexity. A single ADC delivering two separate payloads could be the answer.

  8. AI Is A Tool — Not A Replacement — For Human Innovation In Drug Discovery 9/4/2024

    This attorney provides practical advice. Can artificial intelligence (AI) make drug discovery easier? Yes! Will we lose the human component essential to the innovation culture? No.

  9. Does Targeting Macrophages Hold The Key For Treating Cancer? 8/30/2024

    What is the role of macrophages, macrophage checkpoint inhibitors, and targeting immune receptor CD24 in treating cancer? What’s needed for clinical success in this space? 

  10. Great siRNA Science Or Savvy Business Acumen? You Need Both 8/28/2024

    Silence Therapeutics has two wholly owned siRNA therapies now in clinical trials and one partnered program with AstraZeneca. Silence's CEO discusses the need for good science, making smart business decisions, and cultivating partnerships.