Drug Discovery Featured Articles & Applications

  1. Automated In-Line Buffer Prep Saves Time And Facility Footprint
    2/1/2018

    Buffer preparation is both time-and space-consuming and can easily become a challenge in biomanufacturing. This application note describes a lean approach to buffer preparation by implementing in-line conditioning (IC).

  2. Overcoming Buffer Challenges With In-Line Conditioning
    2/1/2018

    How in-line conditioning (IC) can help reduce the number of hold tanks and floor space needed for buffer preparation and storage.

  3. Continuous Chromatography In Downstream Processing Of A Monoclonal Antibody
    2/1/2018

    In this study, periodic counter current (PCC) chromatography and straight-through processing (STP) technologies were evaluated in a continuous three-step monoclonal antibody (MAb) purification process.

  4. Buffer Management Solutions For Large-Scale Bioprocessing
    2/1/2018

    How outsourcing and technologies such as in-line conditioning (IC) and in-line dilution (ILD) can help prevent resource constraints, save time, and reduce manufacturing footprint and overall cost in buffer preparation.

  5. Complex Molecule Development: Early Considerations To Avoid Failing Later?
    1/26/2018

    How to understand and prepare for challenges early in development to avoid bottlenecks that significantly slow production and delay a drug’s time-to-market.

  6. Purification Workflow For The Production of Highly Pure Recombinant Proteins
    1/24/2018

    This robust purification process provides the product quality, productivity, and economics demanded by today’s downstream manufacturing.

  7. Isolation Of Individual Cells For Single-Cell Analysis
    1/24/2018

    A demonstration of a simple workflow to verify the reliability of the S3e Cell Sorter in sorting single cells.

  8. Automated mAb Workflows: Combining Multidimensional (Multi-D) Purifications With Product Analysis
    1/24/2018

    A demonstration of the development of a robust, high-quality, and automated Multi-D chromatography purification utilizing both tandem and multi-column configurations using ChromLab™ Software on an NGC Chromatography System.

  9. Are You Ready For The Future of Biomanufacturing?
    1/19/2018

    As novel medicines become a larger part of the industry's portfolio, it is critical you secure a supply chain and manufacturing processes that produce drugs in a reliable, cost-effective way. 

  10. What’s New in U.S. Biosimilar-Land?
    1/16/2018

    A lot has been promised with the introduction of biosimilars, but can they really deliver a viable alternative treatment to biologics at a substantial savings?