Drug Discovery Featured Articles & Applications

31. Tapping Into Nature's Pharmacy To Develop Safer Antiseizure Medications? 11/11/2025

    We caught up with Colleen Carpenter-Swanson, Ph.D., University of Richmond, to discuss the use of zebrafish models to investigate whether vitexin can be used in antiseizure medications.

32. How Can We Develop New Treatments For Patients With Early Breast Cancer? 11/10/2025

    Intensity Therapeutics has developed a new approach to treating cancer — a therapy injected directly into tumors that kills cancer and stimulates a potent anticancer immune response.

33. When One Gene Isn't Enough: The Case For Gene-Agnostic Vision Rescue 11/7/2025

    The genetic diversity of retinitis pigmentosa challenges the one-gene-one-therapy model and positions RP as a proving ground for gene-agnostic treatments designed to preserve or restore visual function across genotypes.

34. Notes From A VC: What It Takes To Be Impactful In Longevity Science 11/6/2025

    Impact in longevity science (particularly for cell and gene therapies) is not about chasing the next unicorn; it is about carrying transformative ideas across the threshold of scientific validation, regulatory trust, and societal acceptance.

35. Protein Degraders Redefine ADME And Drug Disposition Dynamics 11/5/2025

    ADME principles have been recently challenged by the emergence of protein degraders, or proteolysis-targeting chimeras (PROTACs), which can benefit from an ABDE framework instead.

36. OpenFold3 Released: Redefining The Limits Of Protein Prediction Models 11/4/2025

    OpenFold3, a biomolecular structure prediction model based on AlphaFold3 was recently released by the OpenFold Consortium, a non-profit AI R&D organization.

37. Returning To Nature: Discovering The Next Generation Of Medicines 11/4/2025

    Researchers at Kapoose Creek Bio are looking to use nature, specifically fungi, to treat mental health and neurodegenerative disorders.

38. How The U.S. Can Beat China In Biotech 11/3/2025

    Lumen Bioscience's Brian Finrow breaks down China's biotech playbook and explores ways the U.S. can adapt it for its own continued success.

39. When Preclinical Models Distort The Patient 11/3/2025

    Drug development's translation doesn’t fail for lack of tools. It fails when those tools remain unaligned. The industry needs a better system, one that integrates the partial truths of each platform into a predictive whole.

40. Makary Talks Faster Drug Reviews, 'Continuous Trials,' DTC Ads 10/31/2025

    Part one of a two-part series on FDA Commissioner Martin Makary, M.D.'s comments at the Gailen Forum in New York City on October 30, 2025.