Drug Discovery Featured Articles & Applications
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The ADC Market To Triple By 2030, Driven By Big Pharma Developments
8/8/2023
After two decades of trial and error in antibody–drug conjugates (ADC) development, the field is poised to deliver a plethora of targeted drugs to treat a wide range of tumor types. Let's take a look at new market research and some notable recent developments in the space.
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The Current & Future Outlook For Precision Medicine In Women’s Health
8/7/2023
The promise of shifting away from a “one size fits all” strategy in women’s health is most clear in advances in breast cancer care, but more recent activity shows precision medicine is possible across many aspects of women’s health outside oncology.
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4 Tips To Leverage Your Ingredient Supplier For Faster Formulation
8/3/2023
Speed to formulation plays a critical role in recouping the investment for a new drug. Many ingredient suppliers have an experienced analytical group and material scientist group, and drug developers should reach out and leverage that expertise with these four strategies.
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Strategic Business Pivoting For Cell & Gene Therapy Startups
8/1/2023
Cell and gene therapy companies need to implement a strategy that helps build a pipeline more quickly and effectively. Let's examine lean startup culture, identifying the signs that your company may need to pivot, and the four primary pivots for more nimble success.
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5 Promising Applications Of RNA Therapeutics
7/28/2023
Ribonucleic acid (RNA), once considered a mere messenger molecule, has now emerged as a versatile tool in the development of novel therapies. In this article, we will delve into the world of RNA therapeutics, exploring their potential and five applications that could impact the future of medicine.
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Engineering Antibodies In A Box?
7/27/2023
Machines aren’t smart enough to engineer optimal, disease-specific antibodies without data that’s properly generated, captured, and structured. That’s why LabGenius Founder Dr. James Field says the key to success is neither human-derived data, nor machine-enabled design. It’s the organizational engineering feat of bringing the two together.
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How Can Genetic Tuning Expand the Reach of Genetic Medicine?
7/26/2023
Epigenome editing, or genetic tuning, is an innovative molecular technology that fine-tunes the expression of genes to a therapeutically appropriate dosage, effectively expanding the reach of genetic medicine beyond the binary on-and-off switches of prior methods. Let's examine this more closely.
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Targeting RNA With Small Molecules
7/25/2023
Beyond mRNA's dogmatic role as the intermediate in gene expression, non-coding RNA play essential roles in transcription regulation, maturation, and translation. This article explores the potential of RNA as a clinically validated avenue for drug development, methods for design and discovery, and implications for the future of medicine.
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6 Emerging Trends In Using Stem Cell Assays
7/24/2023
Stem cell assays allow scientists to assess the self-renewal capacity, proliferation rate, differentiation potential, and other characteristics of stem cells. By understanding how stem cells respond to different conditions, scientists can optimize protocols for therapeutic use. Let's look at six emerging trends in using stem cell assays.
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FDA Finalizes Guidance On Nonclinical Evaluation Of Pharmaceutical Immunotoxicity
7/18/2023
The FDA has now finalized a guidance document on the immunotoxic potential of pharmaceuticals. The FDA builds on current ICH guidance and proposes a two-stage approach. Central to the guidance is using a risk framework.