Drug Discovery Featured Articles & Applications

  1. Periodontitis And Neurological Disease: New Insights For Drug Targeting 6/10/2024

    This article discusses the link between periodontal disease and systemic disorders, focusing most on the association between proteases and neurological dysfunction. Therapeutic measures can target these pathological pathways.

  2. Beware AI Hallucinations 6/7/2024

    As the use of AI increases and expands to new functional areas within biopharmaceutical companies, leaders must understand the risks and mitigate the impact of hallucinations in AI model outputs.

  3. Is Your Intellectual Property Safe With Indian CROs And CDMOs? 6/3/2024

    Startups and Big Pharma companies alike are considering India as an alternative to working with China. Is it safe to do business with India? Let's do a deep dive, with insights from American and Indian attorneys.

  4. Revolutionizing Modifier Gene Therapy Through A Gene-Agnostic Approach 5/29/2024

    Traditional methods reliant on individual gene replacement strategies have limitations. Researchers are now investigating ways to use a single modifier gene to treat an array of diseases.

  5. FDA's Draft Guidance On Safety Testing Of Human Allogeneic Cells For Use In Cell-Based Therapies 5/24/2024

    This article provides a summary and analysis of the FDA's new draft guidance, Safety Testing of Human Allogeneic Cells Expanded for Use in Cell-Based Medical Products. The public comment period ends July 29.

  6. Cannabinoids Show Promise As New Treatment For Alzheimer's Disease 5/18/2024

    Cannabinoids and their innate interaction with the endocannabinoid system, specifically with neuronal functioning, present an attractive therapeutic pathway for Alzheimer's disease, explains Eric Hsu, Ph.D., senior vice president of preclinical research and development at InMed Pharmaceuticals. 

  7. Gene Therapy: How Should We Approach Benefit And Risk? 5/14/2024

    Understanding the benefit-risk ratio is a complex exercise for gene therapies, where there hasn't been sufficient time to understand the long-term risks. How should we approach it?

  8. $25 Million Awards Help Cancer Researchers Make Clinical Trial Inroads 5/9/2024

    Cancer Grand Challenges — a global research initiative cofounded by Cancer Research U.K. and the National Cancer Institute in the U.S. — supports cancer research that aims to answer some of the field’s most dire questions and pertinent needs.

  9. mRNA: The Fourth Pillar Of Pharmaceutical Innovation And Intervention 4/26/2024

    mRNA medicines represent the genesis of a fourth pillar of pharma innovation. While exciting, there are several critical challenges we must solve to strengthen this pillar, including stability and deliverability.

  10. Bucking Convention: How Analog Ibogaine Could Help Conquer CNS Disorders 4/22/2024

    EQUULUS Cofounder and CEO Robert Discordia discusses his company’s pursuit of an analog ibogaine as a potential therapy for CNS disorders.