Drug Discovery Featured Articles & Applications

  1. Understanding The Impact Of An RMP On Patient Risks Using Relational Risk Analysis 5/5/2025

    Using relational risk analysis, let's take a closer look at risk management plans for identifying and managing adverse reactions for administering a new therapy to a patient.

  2. Designing The Next Wave Of T Cell Engagers 5/1/2025

    Abpro's associate director of biology has led programs in immuno-oncology R&D with a focus on therapeutic T cell engagers. We caught up with him to discuss how industry can pave a future for the field.

  3. AI Vs. Humans In Novel Drug Target Identification 4/30/2025

    Artificial intelligence is beginning to replace humans in drug discovery, one expert warns — but the industry isn’t ready for the shift.

  4. A Checklist For Mechanism-Based Potency Testing In Cell Therapy 4/25/2025

    New research concludes that potency cannot be decoupled from a product's mechanism of action because surrogate markers fail to capture functional relevance.

  5. FDA RIFs Might Delay Your Review — Here Are Tips For Mitigating 4/24/2025

    Mounting concerns that FDA reviewers could start missing PDUFA deadlines have put many on edge. The moment calls for defensive and offensive strategies.

  6. Promising Clinical Trial Updates Shared At The American Academy Of Neurology Conference 4/24/2025

    The 2025 American Academy of Neurology (AAN) conference in early April saw some promising clinical trial updates treating Guillain-Barre Syndrome and Huntington’s Disease, CIDP, and ALS.

  7. How To Approach Tech Transfers And Sponsored Life Sciences Research In An AI Age 3/27/2025

    Two IP attorneys examine the patentability of AI-conceived inventions and share tips for technology transfers and sponsored research in pharma/biotech.

  8. Applying AI To Identify Synergistic Drug Combinations For Cancer Treatment 3/14/2025

    By combining drugs/therapies with different mechanisms of action, different pathways in cancer cells can be targeted, potentially leading to improved patient outcomes. Using AI is hastening this research.

  9. Mesenchymal Stem Cells Hold The Key To Treating Degenerative Conditions 3/7/2025

    Mesenchymal stem cells offer a promising path forward in managing complex conditions that are often age-related. What makes MSCs unique and how do they compare to iPSCs?

  10. Understanding The New U.K. MHRA 'Draft Guideline On Individualised mRNA Cancer Immunotherapies' 3/5/2025

    The U.K.'s MHRA has released a new draft guideline outlining best practices for drug product design, CMC, and manufacturing of mRNA cancer immunotherapies using LNP delivery systems. The public comment period ends March 31.