Drug Discovery Featured Articles & Applications

  1. Cost Savings And Speed: The Untapped Value Of A Single-Source Solution
    9/7/2017

    Small and emerging companies face significant challenges in today’s market. This calls for an alternative solution to help them achieve success. One option is a single-source solution, which can eliminate the silos that can often exist in today’s outsourcing paradigm, increasing both communication and speed.

  2. The Next Generation Of Bioprocess Engineering: Bringing A Perspective From The Last Two Decades
    8/25/2017

    The increasing complexity of bioprocess engineering has driven a shift toward cell biology and away from process engineering.  Cell types have become more diverse, the science more complex, and genetic modifications more common, all while products are becoming more targeted and cost effective.   What should we expect to see from industry and academia to keep the field moving forward?

  3. Perfusion – Do’s And Don’ts To Cut Production Costs, Increase Efficiency
    8/25/2017

    Setting up a perfusion process is complex, and getting the best out of it requires an awareness of the do’s and don'ts of the approach.  Design of experiment (DoE) and quality by design (QbD) approaches help the development of a production process that is both cost-effective and high quality.

  4. Batch And Fed Batch Culture — Practical Steps For Better Results
    8/25/2017

    Design of Experiments (DoE) mathematical models can help create the perfect environment for batch and fed batch cultures. Understanding the different criteria  and their interactions with each other can be a key differentiator in the race to get your drug to market. 

  5. Fermentation And Cell Culture: Bringing The Basics To The Fore
    8/25/2017

    Fermentation and cell culture can be carried out in batch or continuous processes.  Reminding ourselves of the basics is vital for the development of more cost-effective and efficient biotech production processes. This article reviews those basics to understand the methods best suited for your development.

  6. Practical Guidelines For Lab-Scale Processing In Volumes <50L
    8/25/2017

    As biotechnology takes a greater role across different industries, a standardized color code system has been created to describe the different roles and applications.

  7. Early CMC Work Sets Groundwork For Regulatory Success
    8/24/2017

    Understand how the more support and guidance small biopharmaceutical companies receive in terms of CMC expertise, the better groundwork it will lay for a successful IND filing.

  8. Dealing With Demand Uncertainty In Biologics
    8/24/2017

    When a biologics company is preparing to launch a new product, its manufacturing capacity forecast is subject to a great deal of uncertainty. Biologics developers must consider scale and volume — in that order.

  9. Streamlined Supply Chain Solutions Boost Efficiency
    8/24/2017

    When customers consolidate their supply chain and use one vendor from drug substance through drug product, it can transform the entire drug development process into a more efficient system.

  10. What You Need To Know To Avoid Costly Delays In Your API Scale-Up
    8/22/2017

    If, in the course of the development process, undesirable effects occur that negatively impact API scale-up, it can prevent a company from delivering a product with reliable quality and efficacy.