Drug Discovery Featured Articles & Applications

  1. Could iPSCs Be The Answer To Treating CNS Disorders? 10/2/2025

    We caught up with Jeffrey M. Brown, Ph.D., MBA, scientific advisor at Neurizon Therapeutics, to discuss how iPSCs could be the key to treating CNS disorders.

  2. Tyra Crystallizing The First Oral FGFR3 Therapy For Achondroplasia 9/30/2025

    Tyra Biosciences is using its SNÅP drug discovery platform to develop dabogratinib, the first oral FGFR3-selective therapy for achondroplasia, currently recruiting patients in Phase 2 trials.

  3. Pros And Cons Of In Silico Target-Drug Dynamics 9/29/2025

    In silico target-drug dynamics offer unprecedented speed, scalability, and cost-efficiency, but there are risk factors of overreliance, regulatory uncertainty, and data bias.

  4. AI Meets Aging: Inside The Longevity Revolution With Insilico Medicine (Part 2) 9/19/2025

    Part 2 of 2 - An Interview with Alex (Aleksandrs Zavoronkovs) Zhavoronkov, Ph.D. , Longevity and drug discovery researcher, Founder, CEO and CBO at Insilico Medicine.

  5. AI Meets Aging: Inside The Longevity Revolution With Insilico Medicine (Part 1) 9/18/2025

    An Interview with Alex Zhavoronkov, Ph.D. Longevity and drug discovery researcher, Founder, CEO and CBO at Insilico Medicine. Founded in 2014, Insilico Medicine, is one of the earliest AI-driven biotech companies and one of the few who have pipeline drugs in Phase II trials.

  6. Expanding A Single Mechanism Through Genetic Logic And Clinical Observation 9/12/2025

    With the right biology, a single mechanism can open multiple clinically meaningful avenues for oncology drug development. Step Pharma CEO discusses their clinical development programs for oncology.

  7. The Death Of A Dogma: David Baltimore And Lessons For Modern Drug Discovery 9/11/2025

    Nobel laureate, David Baltimore passed away at 87 years old, on September 6, 2025. He was widely regarded as a scientific visionary who at just 37, co-discovered reverse transcriptase, an enzyme that flipped molecular biology on its head by showing that genetic information could flow from RNA back to DNA, not just the other way around. 

  8. Building Robust AI Systems For Drug Discovery Requires Epistemic Humility 9/10/2025

    The future of AI in drug discovery lies not in replacing human judgment but in creating systems that enhance it by combining the pattern recognition power of machines with epistemic humility.

  9. Redesigning Oncology Trials Around Tumor Vulnerability: The Rise of WEE1 And DDR Strategies 9/8/2025

    As clinical progress with DNA damage response (DDR) continues to evolve, research must respond with adaptive models, smarter combinations, and biomarker-informed patient selection.

  10. Targeting GRIN Genes In Drug Development To Treat Neurodevelopment Disorders 8/28/2025

    The ability to precisely control the activity of NMDA receptors could play a role in the treatment of a range of neurodevelopmental disorders. We caught up with GRIN Therapeutics' chief medical officer to discuss drug development.