Drug Discovery App CS WP
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Generating A Robust Host Cell Line For A Cell Line Development Platform
11/14/2022
Learn how cell performance within the context of the cell line development workflow was confirmed with the successful isolation of stable, high-producing clones from three model monoclonal antibodies.
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Understanding The Microfluidic Platforms For Scaling Nanoparticle Production
10/13/2022
Learn about the benefits of microfluidics for nanoparticle production over traditional methods as well as scaling nanoparticle production for clinical or industrial use.
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Biacore™ SPR Systems For Titer Analysis Of Adeno-Associated Virus
10/13/2022
We describe the performance of two assays for titer analysis of adeno-associated virus (AAV), serotype 2 and serotype 5, based on surface plasmon resonance (SPR).
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AAV Production In Suspension HEK293 Cells With Single-Use Bioreactors
10/13/2022
Explore how we expanded HEK293/HEK293T suspension cells from small cell culture (20 mL) in shake flasks up to a 10 L culture in a benchtop Xcellerex™ XDR-10 single-use bioreactor system.
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Recombinant Adeno-Associated Virus Type 5 Production Process
10/12/2022
Learn about a scalable process for the production of rAAV using triple plasmid transfection of suspension cells in an animal-derived component-free medium.
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Systems For Shop Floor Automation And Digitization
9/30/2022
We review an automation system that is based on a standard technology platform, with standardized hardware, networking, and software elements and is designed to securely connect to end-user networks.
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Cybersecurity And Product Design Of Automated Systems
9/30/2022
Learn about the importance of cybersecurity for automated equipment, it's weaknesses and risks, and how to mitigate for them by sensible practice and good system design.
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The Power Of Modular Design
9/30/2022
Learn how modular design has the potential to provide a solution for the increasing pressure and demand for biologics.
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The Journey To AAV Production In Suspension – Scaling-Up Your Process
9/27/2022
We present a simple protocol for scaling up AAV production using HEK293 host cells cultured in suspension and under serum-free conditions.
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Advancing A Cell Therapy Drug To The Clinic: Safety Tox Package
9/26/2022
Cytopeutics, a provider of mesenchymal stem cells (MSC) for clinical trials and treatment, needed to conduct safety and tumorigenicity studies in appropriate animal models for its hMSC product.