Drug Discovery App CS WP

  1. A Duplex Assay For Quantification And Qualification Of AAV 5/13/2025

    Adeno-associated virus is a key gene therapy vector. Explore how digital PCR offers precise, standard-free quantification with improved consistency and inhibitor tolerance over traditional qPCR methods.

  2. Analysis Of DNA Integrity And Stability Using Digital PCR 5/13/2025

    Digital PCR offers precise, inhibitor-resistant DNA quantification and genome integrity assessment. Discover how this method enhances accuracy and reproducibility, especially in AAV analysis, using multiplexed targets and Poisson-based calculations.

  3. Rapid Discovery And Characterization Of Monoclonal Antibodies Against The SARS-CoV-2 Delta Spike Protein 4/23/2025

    Delve into the intricate workflow employed for the discovery and characterization of monoclonal antibodies (mAbs) targeting the Delta spike protein.

  4. Proximity Inducers In Drug Discovery - A Perspective On Cooperativity 4/16/2025

    Overcoming the limitations of current proximity inducers requires optimizing cooperativity. Learn how enhancing target affinity can lead to smaller, more effective therapeutics with better safety profiles.

  5. Boost Your Lab's Performance: 3 Ways To Increase Efficiency 4/16/2025

    Maximize your research potential by overcoming workflow bottlenecks. This piece explores flexible strategies for increasing throughput and integrating automation seamlessly into your laboratory operations.

  6. Transfer Of Fed-Batch To Semi-Perfusion Process 4/14/2025

    Continuous processes enhance product quality, yield, and cost savings. Explore transitioning a fed-batch process to perfusion using a small batch bioreactor system to optimize cell culture conditions and comparing performances.

  7. Improve Productivity And Reduce Risk With Biostat® RM 4/14/2025

    Discover how a company overcame cell generation challenges by using a system that achieves a seed ratio of 1:120 and saves four days in seed preparation time.

  8. Extractables And Leachables Assessment For Single-Use Systems 4/14/2025

    Efforts to enhance biopharmaceutical manufacturing focus on boosting production capacity sustainably and economically. Explore how optimizing processes with single-use solutions and monitoring leachables ensures product quality.

  9. Downstream Processing Of A Mid-Scale Lentiviral Vector Batch 4/4/2025

    Explore how tangential flow filtration (TFF) systems streamline lentivirus purification to enhance efficiency and scalability in CAR-T cell production, which is a crucial advancement in cancer immunotherapy.

  10. Assuring Multipotency Of Human Mesenchymal Stem Cells (hMSCs) 4/4/2025

    Stem cell research has revolutionized tissue repair and regenerative medicine. Discover how mesenchymal stem cells play a key role and offer insights into connective tissue repair, immune response, and inflammatory diseases.