Drug Discovery App CS WP
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A Scalable Single-Use Two-Step pDNA Purification Process
3/6/2024
Evaluate the performance of a single-use two-step plasmid purification process, and see how it compares to the existing three-step purification method.
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Five Essentials For Accurate Oligonucleotide Chemistry
3/4/2024
Explore five key areas in oligonucleotide chemistry where improvements will have a huge influence on your synthesis quality.
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Using Automated Spinoculation For CAR T Cell Lentiviral Transduction
2/26/2024
There is a growing demand for closed and automated lentiviral transduction steps in CAR T cell therapy workflows. Learn about a potential solution to address this unmet need.
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A New Way To Perform mAb Capture
2/21/2024
Combining high-productivity chromatography methods and SU affinity membranes delivers a viable alternative to the current packed bed Protein A capture techniques for intensified purification of mAbs.
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Re-Imagining Chromatography: Building Efficient Downstream Processes
2/21/2024
Explore a stepwise approach for integrating process intensification principles into an existing process to increase productivity, reduce costs, and improve process sustainability.
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Integrated And Connected Downstream Processing Of mAbs
2/21/2024
We describe how intensifying two chromatography polishing steps by developing unit operations using Sartobind® Q and CMM HyperCel saves buffer volumes and accelerates the downstream process.
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Optimizing Kinetics Assays To Avoid Avidity Effects
1/31/2024
Considering affinity and avidity early in assay design can ensure the desired assay parameters are achieved. Learn about affinity and avidity and how to recognize and resolve issues that may arise.
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The Key To Accelerating RNA-LNP Drug Development
12/27/2023
Learn about the drug development hurdles that must be overcome to deliver on the promise of mRNA.
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Safer And Faster Conjugation And Purification Of ADCs At 1-20 L Scale
12/5/2023
Explore data demonstrating the successful engineering of a single-use tangential flow filtration system designed to meet the specific requirements of ADC processes.
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Optimizing End-To-End Processes To Reduce Costs And Improve Yields
11/30/2023
Explore the challenges faced by a large CDMO as well as the solutions that were provided to achieve significant time savings, cost savings, and the removal of a major downstream process limitation.