Drug Discovery App CS WP
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The Advantages And Challenges Of Fixed-Dose Combination Products
1/20/2022
Understanding the significant competitive advantages of FDC products and the difficulties and potential pitfalls associated with their development and manufacturing in oral solid dosage forms is critical.
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Scale-Up And Site Transfer Of A Semi-Solid Product For Commercial Launch
1/19/2022
Any changes to the equipment and processes used to produce a semi-solid dosage form may affect the physicochemical characteristics, bioavailability and sensory qualities of the final product.
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Pediatric Dosage Formulation
1/19/2022
A biopharmaceutical company known for its successful anti-infective products for adults sought to reformulate the product into an age-appropriate dosage form for young children and pre-teen patients.
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Fixed Dose Combination Drugs
1/19/2022
A company was seeking a CDMO partner with the expertise and technological capabilities to combine three drug substances into a fixed dose combination product suitable for adult and pediatric dosing.
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Antibody Structure Modeling With Discovery Studio
11/24/2021
Improving the understanding of critical properties of antibodies as early as possible in development and formulation will impact speed and total cost to market. When 3D structures are not available from X-RAY or NMR, 3D in silico models generated are the solution.
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Tackling NTDs At Collaborations Pharmaceuticals - Streamlining Drug Repurposing
11/24/2021
The diversity of the pathogens implicated in NTDs, the relative complexity of their life cycles and their poor tractability in the lab have resulted in a lack of potential therapeutic targets and candidates. By repurposing existing high throughput screening (HTS) data for Ebola and Chagas Disease to create machine learning models which could screen libraries for potential active compounds, especially compounds previously approved by the US FDA for other diseases, they were able to provide safe and efficacious treatments for those who need them most.
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Integrated Predictive Sciences Solutions To Accelerate Drug Discovery And Innovation
11/24/2021
Learn how having the right predictive sciences capabilities integrated into R&D work flows delivers a scientific decision support environment that reduces time and expense, improves quality, enhances collaboration and accelerates innovation in bringing new drugs to market.
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Implementing An Integrated Quality System To Support Business Growth
11/15/2021
A multinational pharmaceutical company with world-wide commercial operations provides contract manufacturing, product development and clinical services to third-party customers. Geographically-dispersed and disconnected business units demanded virtual collaborations that were not easy to support, and many processes throughout the company were manual and disconnected, hindering productivity and collaboration. The company implemented a solution to enable them to deliver high quality, compliant products in an efficient manner.
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Liquid-Liquid Mixing Without Vortex Formation
11/12/2021
This application note describes liquid-liquid homogenization conditions which meet these requirements at various filling levels in four types of mixers.
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Trends In Single-Use Mixing Technologies
11/12/2021
Here we present an overview of the current mixing technology landscape driven by the need for versatile biomanufacturing platforms with increased productivity.