Drug Discovery App CS WP

  1. Media And Buffer Mixing Using The Xcellerex™ Magnetic Mixer 6/19/2024

    A common requirement for media and buffer preparation in biopharma processing is powder-liquid mixing. Review the performance of a 3000 L single-use mixing system for preparing aqueous solutions.

  2. Determining The Power Numbers For A Single-Use Mixing System 6/19/2024

    In designing a mixing process for scale-up, the power number is a critical parameter. Explore the determined power numbers for a single-use mixer at various mixing speeds and fill levels.

  3. Automated Cell Washing And Formulation In CAR T Cell Therapy Manufacturing 6/14/2024

    Explore data collected from a study utilizing healthy donors in a typical CAR T cell processing workflow without a transduction step from a cross-site validation study.

  4. Revolutionizing Drug Discovery From "Undruggables" To AI 6/10/2024

    Explore four current trends in drug discovery, how each trend addresses some of the most crucial challenges in drug discovery, and the obstacles to their widespread adoption.

  5. A Hybrid Modeling Approach To Accelerate Media And Feed Development 6/7/2024

    Explore the outcomes of a study focusing on building a mechanistic model to determine the growth kinetics of a CHO-based process producing a mAb.

  6. Considerations For Developing The Recirculation/Perfusion Process 6/6/2024

    Learn about the recirculation and perfusion processes made possible by single-use, fixed-bed bioreactors designed for scaling up adherent cell culture processes.

  7. A Solution For The Scale-Up Of Multi-Column Chromatography 6/3/2024

    Explore results from a study scaling up a monoclonal antibody (mAb) capture process utilizing the Resolute® BioSMB platform.

  8. CHO Media Screening Success Using Benchmarking Studies 6/3/2024

    Explore the challenges of media screening and a straightforward approach for saving time, reducing risks, and improving outcomes.

  9. A Checklist For Efficient And Reliable Gene Therapy Manufacturing 6/3/2024

    Gain insight into how to design and execute an efficient upstream AAV production process, and follow the checklist within to ensure all appropriate factors are considered at each phase of drug development.

  10. Optimizing Aliquoting For Robust Cell And Gene Therapy Processes 6/3/2024

    Explore the challenges of liquid handling in cell and gene therapy processes as well as innovative solutions to simplify aliquoting in modern bioprocesses.