Drug Discovery App CS WP

  1. Purification And Solubilization Of Membrane Proteins For Cryo-EM Studies 1/29/2025

    See how Cube Biotech and MIT researchers used dynamic light scattering (DLS) and nano differential scanning fluorimetry (nanoDSF) to find the best nanodisc conditions for three membrane proteins.

  2. Achieve Highly Sensitive And Precise Binding Affinity Measurements Without Disrupting Protein Conformation 1/29/2025

    Membrane proteins are vital for drug discovery, but traditional techniques can disrupt their structure. This study showcases a new method that maintains native conformation during analysis.

  3. A Toolkit For Unraveling Protein Expression Patterns 1/6/2025

    Learn about a method that utilizes monoclonal antibodies and flow cytometry to analyze the metabolic state of individual immune cells, advancing immune research and immunotherapy.

  4. Advancing Drug Safety And Improving R&D Productivity With The Liver-Chip S1 12/10/2024

    Explore how the Emulate Liver-Chip S1 revolutionizes predictive toxicology by mimicking human liver biology, achieving superior sensitivity and specificity.

  5. Depth Filters For The Clarification Of AAV 11/27/2024

    Explore study results demonstrating the ability of Sartoclear® depth filters to deliver high performance for AAV clarification, ensuring scalability, high recovery rates, and robust filtration.

  6. Electroporation Enables Efficient Antibody Discovery By Mammalian Display 11/22/2024

    Therapeutic antibody developers leverage mammalian display to identify promising candidates. Electroporation enables superior sequence diversity, enhanced library coverage, and streamlined workflows.

  7. A Human-Relevant Model Of The Liver Sinusoid 11/7/2024

    This organ-on-a-chip model minimizes drug absorption while maintaining the essential architecture. Explore the specifications of this product engineered to model the human liver.

  8. Perspectives On Performance, Scalability, And Regulatory Compliance 10/28/2024

    Here, we discuss the challenges and solutions for cell and gene therapies, focusing on performance, scalability, and regulatory compliance to accelerate commercialization and improve patient access.

  9. Optimizing Time And Cost Efficiency In Cell Line Development 10/28/2024

    Discover a system that automates mAb purification, reducing time and costs in cell line development while improving reproducibility, with faster processing than traditional methods.

  10. Facilitating Efficient Clone Selection And Enabling High-Throughput Clarification And Purification Processes 10/28/2024

    Discover a combination that enables efficient clone selection and automated purification, improving bioprocessing speed, and accelerating biotherapeutic development.