Drug Discovery App CS WP

  1. Zero To Final Fill: How HUGEL Implemented Its First Single-Use Lines 8/6/2025

    As regulations tighten, biomanufacturers are adopting single-use tech to boost compliance, reduce labor, and streamline fill-finish operations from the ground up.

  2. Optimizing CHO Cell Culture Using A Design Of Experiments Approach 8/6/2025

    Learn how researchers optimized CHO cell culture to boost IgG1 titer to 5.8 g/L and improve viability, which cut development time from 14 days to 12 while enhancing productivity.

  3. Pre-Clinical Risk Assessment Of PCSK9 Guide RNAs 8/5/2025

    Learn how a comprehensive, variant-aware screening workflow for therapeutic gene editing can identify and nominate the most favorable guide RNAs for clinical development.

  4. Rapid Production Of Assay Ready Cells For GPCR Drug Discovery 7/29/2025

    Accelerate drug discovery by leveraging transiently transfected assay-ready cells. This method improves assay sensitivity and reduces variability for GPCRs.

  5. A Novel Cell-Based Assay For Ubiquitin Drug Discovery 7/29/2025

    Learn about a novel cell-based assay that can advance ubiquitin ligase drug discovery. This high-throughput method simplifies assay development, saving time and resources.

  6. High-Throughput Screening Of Ion Channel Variants Using Automated Patch Clamp Recordings In Assay Ready Cells 7/29/2025

    High-throughput screening of KCNQ2 ion channel variants provides insights into epilepsy and treatment responses. This validated method supports rapid characterization for precision medicine.

  7. Risk Assessment Services Align With FDA Guidance For Gene-Edited Human Gene Therapy Products 7/29/2025

    Navigate the FDA's gene therapy guidelines with advanced risk assessment strategies. Optimize gene editing and ensure regulatory alignment for safer, more effective therapies.

  8. Mammalian Display Method For The Development Of Enhanced Affinity TCR-Based Biologics 7/29/2025

    Discover how mammalian display enhances T cell receptor-based cancer therapies. This method improves antigen affinity and reduces immunogenicity for more effective treatments.

  9. Electroporation Enables Efficient Antibody Discovery By Mammalian Display 7/29/2025

    Achieve greater sequence diversity and library coverage in antibody discovery. Learn about an approach enables reproducible and scalable transfections, leading to the identification of better antibody candidates.

  10. Development Of A Landing-Pad CHO Cell Line For Mammalian Display 7/29/2025

    A single-site "landing pad" CHO cell line simplifies the creation of mammalian display libraries, enabling consistent, single-copy integration of target sequences for biologic drug discovery.