Drug Discovery App CS WP

  1. How To Successfully Isolate Your T Cells 10/7/2024

    Explore the results of a study focusing on the early stages of the CAR T cell workflow, specifically the initial washing of leukapheresis followed by the isolation of T cells.

  2. Production Of A Highly Concentrated Monoclonal Antibody 10/4/2024

    The production of a highly concentrated monoclonal antibody requires many process steps. Discover how to achieve a final mAb concentration above 200 g/L while maintaining critical quality attributes.

  3. AAV Empty/Full Ratio Assessment Using The Octet® AAVX Biosensors 9/27/2024

    Learn about a rapid, high-throughput method for determining the E/F ratio in the AAV drug product that is well-suited for screening both crude and purified AAV samples.

  4. Rapid, Automated, At-Line Adenovirus Quantitation 9/27/2024

    Gain insight into how a high-throughput capsid assay for rapid AV quantification was developed using an innovative Bio-Layer Interferometry (BLI) platform that offers high precision and reliability.

  5. Standardize Flow Cytometry Data With Easy Assay Transfer Across Sites 9/25/2024

    Gain insight into how a global pharmaceutical company successfully transferred their cell therapy assays across international locations.

  6. Simplified Workflow Using Automated Instrument Setup And Compensation On The BD FACSLyric™ Flow Cytometer 9/25/2024

    Examine the usability and performance capabilities of a system that provides a streamlined flow cytometry workflow, from instrument initialization to data acquisition and analysis.

  7. Immunophenotyping Of Normal Whole Blood Using A 12-Color BD Horizon™ Chroma Research Panel On The BD FACSDuet™ Premium Sample Preparation System Integrated With The BD FACSLyric™ Flow Cytometer 9/25/2024

    In this study, a fully automated workflow utilizing the BD FACSDuet™ Premium Sample Preparation System integrated with the BD FACSLyric™ Flow Cytometer was assessed and compared to manual processing.

  8. Evaluating The Expression Patterns Of Multiple Inhibitory Receptors 9/25/2024

    Discover how an innovative approach to interpreting T-cell exhaustion and inhibitory receptor expression is paving the way for innovative therapeutic approaches aimed at rejuvenating T-cell function.

  9. Biosensors For Rapid And Direct Quantitation Of AAV Capsids 9/23/2024

    Examine the performance of a biosensor for AAV capsid titer measurement that offers high-precision, broad AAV serotype binding specificity, and more.

  10. Extractables In Single-Use Systems Used In ADC Manufacturing 9/23/2024

    To address concerns about using organic solvents in the ADC process, extractables studies were conducted on a disposable chromatography column housing and two different disposable flow paths.