Drug Discovery App CS WP

  1. Reliable Proliferation And Differentiation Of Desired T Cell Subpopulations 10/28/2024

    This study evaluates a cost-effective alternative to Proleukin® for expanding T cells that demonstrates comparable performance across cell viability, subpopulation ratios, and clinical consistency.

  2. Electroporation Enables The Efficient, Scalable Packaging Of CRISPR-Cas9 RNPs In Virus-Like Particles 10/18/2024

    Discover how electroporation technology enables efficient, scalable production of CRISPR-Cas9 VLPs with high editing activity in both adherent and suspension HEK293 cells.

  3. Enhancing Process And QC For Multi-Column Chromatography 10/16/2024

    Explore two innovative technologies that address major purification challenges in DSP: continuous multi-column chromatography and advanced chromatography or liquid chromatography-mass spectrometry.

  4. Resolute® BioSC Pilot: Designed For Effective And Consistent Chemical And Microbiological Cleaning 10/10/2024

    Issues related to cleaning and cleaning validation are some of the most common concerns that arise in FDA Warning Letters. Discover how to ensure you pass your cleaning validation tests.

  5. Achieving Optimal CAR-T Cell Generation 10/9/2024

    Discover the innovative methods behind CAR-T cell production, from custom plasmid design to lentiviral vector transduction, and explore their potential in revolutionizing cancer treatment.

  6. AAV Empty/Full Ratio Assessment Using The Octet® AAVX Biosensors 9/27/2024

    Learn about a rapid, high-throughput method for determining the E/F ratio in the AAV drug product that is well-suited for screening both crude and purified AAV samples.

  7. Rapid, Automated, At-Line Adenovirus Quantitation 9/27/2024

    Gain insight into how a high-throughput capsid assay for rapid AV quantification was developed using an innovative Bio-Layer Interferometry (BLI) platform that offers high precision and reliability.

  8. Standardize Flow Cytometry Data With Easy Assay Transfer Across Sites 9/25/2024

    Gain insight into how a global pharmaceutical company successfully transferred their cell therapy assays across international locations.

  9. Simplified Workflow Using Automated Instrument Setup And Compensation On The BD FACSLyric™ Flow Cytometer 9/25/2024

    Examine the usability and performance capabilities of a system that provides a streamlined flow cytometry workflow, from instrument initialization to data acquisition and analysis.

  10. Immunophenotyping Of Normal Whole Blood Using A 12-Color BD Horizon™ Chroma Research Panel On The BD FACSDuet™ Premium Sample Preparation System Integrated With The BD FACSLyric™ Flow Cytometer 9/25/2024

    In this study, a fully automated workflow utilizing the BD FACSDuet™ Premium Sample Preparation System integrated with the BD FACSLyric™ Flow Cytometer was assessed and compared to manual processing.