Drug Discovery App CS WP
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Expansion Of Specific Lymphocytes With A Xeno-Free, Serum-Free Medium
4/29/2024
Explore the advantages of utilizing a xeno- and serum-free medium for the targeted expansion of cell subpopulations without the addition of serum.
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Bulk Filling Of Drug Substance | Accurate Aliquoting
4/24/2024
Bulk filling drug substances in traditional facilities is often a lengthy, manual process where operators are relied upon to adjust pump controls to achieve accurate filling. This method, spanning multiple shifts, increases process risk through errors that can compromise accuracy.
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Evaluating CAR T-Cell Therapy Vascular Recruitment, Trafficking, And Killing
4/24/2024
Learn about a more human-relevant platform that enables researchers to assess the trafficking and killing efficiency of immunotherapy as well as the proof-of-concept of immuno-oncology co-therapy.
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Optimizing Human iPSC Aggregate And Organoid Production For Bioprinting
4/17/2024
This study aimed to identify the optimal cell culture conditions to yield high cell density and maintain high cell viability with consistent aggregate morphology and pluripotency marker expression.
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Evaluating On-Target/Off-Tumor Effects Of Cancer Immunotherapies
4/9/2024
A promising class of engineered T-cell engaging bispecific antibodies (TCBs) is revolutionizing cancer treatment, but safety concerns persist. Organs-on-Chips offer a human-relevant solution.
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Exploring Neuroinflammation, Neurodegeneration With A Brain Organ-Chip
4/9/2024
Examine how Organ-on-a-Chip technology, accurately mimicking human neuroinflammation, offers promising human-relevant avenues for neurodegenerative disease research and therapeutic development.
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Studying Gut Inflammation And Barrier Disruption With Organ-On-A-Chip Technology
4/9/2024
See how the Colon Intestine-Chip has been employed to model cytokine-mediated inflammation and barrier disruption in the intestine.
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Predicting Human Liver Damage With A More Accurate In Vitro Hepatotoxicity Assay
4/9/2024
This study explores whether a species-specific, multicellular, in vitro hepatotoxicity assays utilizing Liver-Chips can provide a greater understanding of hepatotoxicity mechanisms than animal models.
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Investigating Key Mechanisms Of Parkinson's With A Brain-On-A-Chip
4/9/2024
Efforts to develop a dynamic “brain-on-a-chip” model that closely resembles the human substantia nigra could be applied to study mechanisms of Parkinson’s disease.
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A Better Immune Response To Vaccination: Using Lymphoid Follicle Organ-Chips
4/9/2024
Discover a first-of-its-kind human LF-Chip containing B, T, plasma and antigen-presenting cells to test functional immunization responses to vaccines and adjuvants in vitro.