Drug Discovery App CS WP

  1. Perspectives On Performance, Scalability, And Regulatory Compliance 10/28/2024

    Here, we discuss the challenges and solutions for cell and gene therapies, focusing on performance, scalability, and regulatory compliance to accelerate commercialization and improve patient access.

  2. Optimizing Time And Cost Efficiency In Cell Line Development 10/28/2024

    Discover a system that automates mAb purification, reducing time and costs in cell line development while improving reproducibility, with faster processing than traditional methods.

  3. Facilitating Efficient Clone Selection And Enabling High-Throughput Clarification And Purification Processes 10/28/2024

    Discover a combination that enables efficient clone selection and automated purification, improving bioprocessing speed, and accelerating biotherapeutic development.

  4. Reliable Proliferation And Differentiation Of Desired T Cell Subpopulations 10/28/2024

    This study evaluates a cost-effective alternative to Proleukin® for expanding T cells that demonstrates comparable performance across cell viability, subpopulation ratios, and clinical consistency.

  5. Enhancing Process And QC For Multi-Column Chromatography 10/16/2024

    Explore two innovative technologies that address major purification challenges in DSP: continuous multi-column chromatography and advanced chromatography or liquid chromatography-mass spectrometry.

  6. Resolute® BioSC Pilot: Designed For Effective And Consistent Chemical And Microbiological Cleaning 10/10/2024

    Issues related to cleaning and cleaning validation are some of the most common concerns that arise in FDA Warning Letters. Discover how to ensure you pass your cleaning validation tests.

  7. Achieving Optimal CAR-T Cell Generation 10/9/2024

    Discover the innovative methods behind CAR-T cell production, from custom plasmid design to lentiviral vector transduction, and explore their potential in revolutionizing cancer treatment.

  8. How To Successfully Isolate Your T Cells 10/7/2024

    Explore the results of a study focusing on the early stages of the CAR T cell workflow, specifically the initial washing of leukapheresis followed by the isolation of T cells.

  9. Production Of A Highly Concentrated Monoclonal Antibody 10/4/2024

    The production of a highly concentrated monoclonal antibody requires many process steps. Discover how to achieve a final mAb concentration above 200 g/L while maintaining critical quality attributes.

  10. AAV Empty/Full Ratio Assessment Using The Octet® AAVX Biosensors 9/27/2024

    Learn about a rapid, high-throughput method for determining the E/F ratio in the AAV drug product that is well-suited for screening both crude and purified AAV samples.