Drug Discovery App CS WP

  1. Standardize Scale-Up And Reduce Time To Market With Mixing Cartridges 7/21/2023

    Despite the momentum of the RNA-LNP therapeutic market, significant manufacturing challenges remain. However, the right mixing could solve three of these key challenges regarding instrumentation.

  2. Alkaline Stability Of Modern Protein A Chromatography Resins 7/12/2023

    Explore results from a resin lifetime study with over 150 cycles, using clarified cell harvest in every cycle, which has been performed to evaluate the alkaline stability of three protein A resins.

  3. Protein L Affinity Resin Is Ready To Move To Manufacturing 7/12/2023

    Discover a protein L affinity chromatography resin that is well suited for use in biomanufacturing and offers increased binding capacities compared to other resins.

  4. AAV Full/Empty Capsid Separation Using Mechanistic Modeling 5/1/2023

    In this study, we used mechanistic modeling to investigate how AAV-resin interactions are affected when MgCl2 is used as an elution additive.

  5. Recombinant Protein Purification Optimization With HIC 5/1/2023

    A step-by-step high-throughput process development (HTPD) workflow to determine the optimal resin and initial conditions for hydrophobic interaction chromatography (HIC).

  6. Alkaline Stability Of Fc And VH3 Binding In Protein A Resins 5/1/2023

    In this study, we looked at how different antibody binding sites of a protein A ligand are affected by cleaning in place (CIP).

  7. Controlling Trace Impurities In Chemically Defined Media 4/10/2023

    Discover a novel approach for manufacturing chemically defined media with precision control of trace impurities that utilizes innovative raw material analysis, data analytics, and a proprietary algorithm.

  8. How Can The Industry Drive Down The Cost Of Viral Gene Therapies? 4/5/2023

    This article discusses how a combination of optimizing your process development, and process intensification can help drive the cost of dose down.

  9. Depth Filtration Devices For Cell Cultures, Fermentation Broths, And Cell Lysates 3/27/2023

    Typically, devices containing depth media filters can offer more efficient filtration. Browse depth filtration products and devices for the downstream processing of cell culture solutions, fermentation broths, and lysates.

  10. Partnering On An Innovative Hydrogel-Based Treatment For Glioblastoma 3/22/2023

    Treatments for glioblastoma multiforme (GBM) are in high demand. Learn more about the new possibilities for increased dosing and diffusion capabilities offered by nanoformed APIs.