Drug Discovery App CS WP

  1. Preclinical Technique To Assess Targeted Therapies For Primary, Metastatic NSCLC 9/13/2025

    To enable comprehensive evaluation of therapies targeting both primary and metastatic tumors, we've developed dual-disease xenograft models using bioluminescence imaging (BLI).

  2. Characterize Your PROTAC Hook Effect With Flexible In-Solution Affinity Measurements 9/3/2025

    Characterizing the PROTAC hook effect is crucial for selecting candidates with enhanced cooperativity. Gain confidence with flexible, in-solution affinity measurements that reveal key biophysical parameters and align with established three-component binding models.

  3. Aggregation In Antibody-Drug Conjugates: Causes And Mitigation 9/1/2025

    Discover how early intervention in ADC development can streamline clinical progress, ensure stability and safety, and accelerate commercialization with expert guidance.

  4. Time To Intensify: Taking mAb Manufacturing To The Next Level 8/19/2025

    Explore how process intensification can revolutionize monoclonal antibody manufacturing to boost productivity, cut costs, and enhance sustainability with scalable strategies and real-world results.

  5. Cell Line Development For Bispecific Antibodies 8/18/2025

    See how the recently described cell line development paradigm shift, enabled by the Leap-In transposon platform, can extend to the development of bispecific monoclonal antibody-producing cell substrates.

  6. Zero To Final Fill: How HUGEL Implemented Its First Single-Use Lines 8/6/2025

    As regulations tighten, biomanufacturers are adopting single-use tech to boost compliance, reduce labor, and streamline fill-finish operations from the ground up.

  7. Optimizing CHO Cell Culture Using A Design Of Experiments Approach 8/6/2025

    Learn how researchers optimized CHO cell culture to boost IgG1 titer to 5.8 g/L and improve viability, which cut development time from 14 days to 12 while enhancing productivity.

  8. Pre-Clinical Risk Assessment Of PCSK9 Guide RNAs 8/5/2025

    Learn how a comprehensive, variant-aware screening workflow for therapeutic gene editing can identify and nominate the most favorable guide RNAs for clinical development.

  9. Balancing Protein A Resin Cost, Performance, And Productivity 7/31/2025

    Optimizing input parameters like DBC, flow rate, and resin durability is key to boosting productivity in downstream bioprocessing. Discover how to tailor resin choices to meet your specific process requirements.

  10. Rapid Production Of Assay Ready Cells For GPCR Drug Discovery 7/29/2025

    Accelerate drug discovery by leveraging transiently transfected assay-ready cells. This method improves assay sensitivity and reduces variability for GPCRs.