Drug Discovery App CS WP

  1. A Novel Cell-Based Assay For Ubiquitin Drug Discovery 7/29/2025

    Learn about a novel cell-based assay that can advance ubiquitin ligase drug discovery. This high-throughput method simplifies assay development, saving time and resources.

  2. High-Throughput Screening Of Ion Channel Variants Using Automated Patch Clamp Recordings In Assay Ready Cells 7/29/2025

    High-throughput screening of KCNQ2 ion channel variants provides insights into epilepsy and treatment responses. This validated method supports rapid characterization for precision medicine.

  3. Risk Assessment Services Align With FDA Guidance For Gene-Edited Human Gene Therapy Products 7/29/2025

    Navigate the FDA's gene therapy guidelines with advanced risk assessment strategies. Optimize gene editing and ensure regulatory alignment for safer, more effective therapies.

  4. Mammalian Display Method For The Development Of Enhanced Affinity TCR-Based Biologics 7/29/2025

    Discover how mammalian display enhances T cell receptor-based cancer therapies. This method improves antigen affinity and reduces immunogenicity for more effective treatments.

  5. Electroporation Enables Efficient Antibody Discovery By Mammalian Display 7/29/2025

    Achieve greater sequence diversity and library coverage in antibody discovery. Learn about an approach enables reproducible and scalable transfections, leading to the identification of better antibody candidates.

  6. Development Of A Landing-Pad CHO Cell Line For Mammalian Display 7/29/2025

    A single-site "landing pad" CHO cell line simplifies the creation of mammalian display libraries, enabling consistent, single-copy integration of target sequences for biologic drug discovery.

  7. Ultra-High-Throughput Biophysical Screening Of MEK1 7/28/2025

    Discover an ultra-high-throughput biophysical screening method for MEK1 inhibitors, offering rapid and accurate hit identification with minimal sample use.

  8. Optimized Urine Liquid Biopsy Workflow 7/14/2025

    Urine-derived cell-free DNA is revolutionizing liquid biopsy research to offer a non-invasive, accessible tool for early disease detection, monitoring, and comprehensive diagnostics across oncology.

  9. Liquid Biopsy-Based Detection Of PIK3CA Mutations From cfDNA 7/14/2025

    Discover how ultra-sensitive digital PCR workflows use an innovative system to enable precise detection of rare PIK3CA mutations in cfDNA and advance personalized cancer treatment.

  10. Detect Ultra-Rare Variants In cfDNA From Liquid Biopsy Samples 7/14/2025

    Liquid biopsy, powered by next-generation sequencing, is transforming precision oncology to offer real-time, non-invasive insights into tumor genetics, which revolutionizes how we monitor and manage cancer.