Drug Discovery App CS WP

31. A Hybrid Modeling Approach To Accelerate Media And Feed Development 6/7/2024

    Explore the outcomes of a study focusing on building a mechanistic model to determine the growth kinetics of a CHO-based process producing a mAb.

32. Considerations For Developing The Recirculation/Perfusion Process 6/6/2024

    Learn about the recirculation and perfusion processes made possible by single-use, fixed-bed bioreactors designed for scaling up adherent cell culture processes.

33. A Solution For The Scale-Up Of Multi-Column Chromatography 6/3/2024

    Explore results from a study scaling up a monoclonal antibody (mAb) capture process utilizing the Resolute® BioSMB platform.

34. CHO Media Screening Success Using Benchmarking Studies 6/3/2024

    Explore the challenges of media screening and a straightforward approach for saving time, reducing risks, and improving outcomes.

35. A Checklist For Efficient And Reliable Gene Therapy Manufacturing 6/3/2024

    Gain insight into how to design and execute an efficient upstream AAV production process, and follow the checklist within to ensure all appropriate factors are considered at each phase of drug development.

36. Optimizing Aliquoting For Robust Cell And Gene Therapy Processes 6/3/2024

    Explore the challenges of liquid handling in cell and gene therapy processes as well as innovative solutions to simplify aliquoting in modern bioprocesses.

37. The Advantages Of A Blended Learning Approach In Operator Training 5/30/2024

    Explore blended learning and its advantages over traditional operator training methods, which often reduce training to a repetitive but necessary checklist of reading and acknowledging procedures.

38. Adapting Single-Use Chromatography To Manufacturing Scale 5/16/2024

    Explore strategies for accommodating the ever-increasing upstream titers and volumes to prevent downstream purification from becoming a bottleneck.

39. Accelerated API Manufacturing: Combining All Process Development Stages 5/16/2024

    During early-stage development, utilize the key considerations outlined in this paper to avoid common pitfalls and expedite the transition from molecule to market.

40. Compound Library Consortium 5/16/2024

    Explore how a novel approach to enhancing drug discovery efforts can significantly improve the chances of identifying promising drug candidates, ultimately accelerating the path from discovery to development.