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1. Expanding A Single Mechanism Through Genetic Logic And Clinical Observation 9/12/2025

   With the right biology, a single mechanism can open multiple clinically meaningful avenues for oncology drug development. Step Pharma CEO discusses their clinical development programs for oncology.

2. How Single-Use Technologies Are Simplifying Contamination Control 9/10/2025

   Learn how single-use technologies help reduce contamination risks and support compliance with updated EU GMP Annex 1 guidelines for aseptic processing and sterile drug manufacturing.

3. Building Robust AI Systems For Drug Discovery Requires Epistemic Humility 9/10/2025

   The future of AI in drug discovery lies not in replacing human judgment but in creating systems that enhance it by combining the pattern recognition power of machines with epistemic humility.

4. Redesigning Oncology Trials Around Tumor Vulnerability: The Rise of WEE1 And DDR Strategies 9/8/2025

   As clinical progress with DNA damage response (DDR) continues to evolve, research must respond with adaptive models, smarter combinations, and biomarker-informed patient selection.

5. Characterize Your PROTAC Hook Effect With Flexible In-Solution Affinity Measurements 9/3/2025

   Characterizing the PROTAC hook effect is crucial for selecting candidates with enhanced cooperativity. Gain confidence with flexible, in-solution affinity measurements that reveal key biophysical parameters and align with established three-component binding models.

6. Aggregation In Antibody-Drug Conjugates: Causes And Mitigation 9/1/2025

   Discover how early intervention in ADC development can streamline clinical progress, ensure stability and safety, and accelerate commercialization with expert guidance.

7. Targeting GRIN Genes In Drug Development To Treat Neurodevelopment Disorders 8/28/2025

   The ability to precisely control the activity of NMDA receptors could play a role in the treatment of a range of neurodevelopmental disorders. We caught up with GRIN Therapeutics' chief medical officer to discuss drug development.

8. Can America's Retreat On mRNA Be Europe's Opportunity? 8/28/2025

   With HHS winding down mRNA vaccine development under BARDA, could Europe seize the opportunity to lead in mRNA innovation? Exploring the policy shift's implications.

9. The OBBBA: Biopharmas Unlock R&D Expensing, Global Tax Efficiencies 8/28/2025

   Biopharma innovators may soon see major tax breaks thanks to the One Big Beautiful Bill Act (OBBBA). The new legislation introduces targeted tax incentives designed to strengthen domestic R&D and capital investment.

10. AI Plus The Scientific Method Might Reinvent Drug Discovery 8/26/2025

    In the absence of good data, clear hypotheses, and experimental feedback, AI’s outputs can quickly become unreliable. The solution lies in integrating AI and the scientific method.