Downloads
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Inside Cellular Rejuvenation Therapies for Age-Related Diseases with Life Biosciences' Sharon Rosenzweig-Lipson, Ph.D.
3/14/2024
On this episode of Cell & Gene: The Podcast, Host Erin Harris talks to Life Biosciences' CSO, Sharon Rosenzweig-Lipson, Ph.D., about the Boston-based biotech's cellular rejuvenation therapies for the treatment of age-related diseases.
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Modeling Inflammation-Specific Immune Cell Recruitment
3/13/2024
Traditional models for studying inflammatory bowel disease (IBD) often fall short. See how the Colon Intestine-Chip was used to model the progression of IBD driven by immune cells more completely.
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Advanced In Vitro Duodenal Model For Toxicity Assessment
3/13/2024
Here, we review how an advanced in vitro model closely aligned with the human duodenum was utilized to evaluate the toxicity of indomethacin, a known gastrointestinal toxicant.
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Cytokine-Mediated Inflammation In A Relevant Preclinical Model
3/13/2024
Learn about a novel preclinical model and how it enables the study of cytokine-mediated barrier inflammation mechanisms as well as the efficacy of anti-inflammatory therapeutics.
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The Application Of The Species-Specific Liver-Chip In Predicting Hepatoxicity
3/13/2024
An evaluation of 150 drug candidates causing adverse events in humans revealed testing in rats and dogs predicted only 71% of toxicities in humans. Discover a solution to this translational challenge.
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Benchtop TFF System Enabling Single Pass Continuous Diafiltration
3/13/2024
Learn in detail about a benchtop tangential flow filtration system that enables highly efficient diafiltration of biomolecular solutions in a continuous, single pass process.
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Self-Contained TFF Cassettes For Diafiltration In A Single Pass
3/13/2024
Explore detailed insights into self-contained tangential flow filtration cassettes for continuous diafiltration with low buffer consumption matching conventional diafiltration performance in one pass.
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Hybrid Modeling Approach For Rapid Clone Selection In Perfusion Processes
3/13/2024
Discover a hybrid modeling approach designed for rapid clone selection in perfusion processes that can help you determine optimal process characteristics and growth conditions, expediting development.
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Identify And Mitigate Absorption Risks With PBPK Modeling
3/12/2024
See how PBPK models combined with custom and off-the-shelf in vitro tools and solubility enhancement expertise can reduce the need for drug product reformulation or repeated preclinical or clinical studies.
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Sterilizing Grade Filter Performance With Biologic Drugs
3/11/2024
Here, we analyze the throughput performance of sterilizing grade filters across moderate-to-high concentrations of mAbs and immunoglobulins and demonstrate how filter selection can impact your process.