Newsletter | June 30, 2026

06.30.26 -- A New De Novo Protein Design Platform For GPCR Drug Discovery

FEATURED EDITORIAL

A New De Novo Protein Design Platform For GPCR Drug Discovery

By Ray Dogum, chief editor, Drug Discovery Online

Skape Bio and UW created an AI-driven platform to design miniproteins that modulate GPCRs in living cells, opening new paths for biologic drug discovery.

Advancing Spatial Multiomics For Discovery: From Promise To Practice

By Ray Dogum, chief editor, Drug Discovery Online

Spatial multiomics offers extraordinary biological insight, but high costs, tissue bottlenecks, and unclear clinical relevance still limit its reach.

Discovery Dialogues: Stef van Grieken, CEO, Cradle Bio

By Ray Dogum, chief editor, Drug Discovery Online

DDO caught up with Stef van Grieken, CEO of Cradle Bio, which uses AI to speed protein design, putting tools in scientists’ hands. Gains in lead optimization are clear, but safety CMC and tough targets remain key challenges.

INDUSTRY INSIGHTS

Enhanced Lentiviral Vector Characterization Using Digital PCR

Poster | By Miroslav Vraneš, Anne Schieren, Philipp Rink, et al., QIAGEN

Digital PCR offers a precise, scalable approach to lentiviral vector characterization, enabling reliable genome titer, vector copy number, and RCL detection while reducing variability.

Integrating High-Content Imaging With Traditional Plate-Based Screening

Poster | By Nick Lenhard, Adam McCabe, Clark Driscoll, Gregory Williams, Ph.D., Curia

Gain mechanistic insights beyond traditional viability assays, revealing nuanced cellular phenotypes and strengthening early drug discovery decisions without sacrificing throughput or efficiency.

Simultaneous Spray Drying: Dry Powder Inhaler Combination Formulations

Webinar | Lonza

The simultaneous spray drying of multiple ingredients is a powerful technique for making inhaled products with multiple actives. Examine how novel techniques can make these products a reality.

Utilizing The Colon Intestine-Chip To Investigate Mechanisms Of GI Disease

Webinar | Emulate

What are the application and benefits of Organ-Chips and what makes them superior to organoids in the study of GI-related diseases?

How To Deal With The Complexity Of Drugs In Clinical Development

Article | Lonza

The increasing complexity of the drugs currently in clinical development has created mounting pressure for companies hoping to surmount the myriad challenges that typify these therapeutic modalities.

SOLUTIONS

Fast And Reliable Real-Time Imaging

BD Biosciences

Process, Analyze, And Report All Your Analytical Data In One Interface

Revvity Signals Software, Inc.