Drug Discovery Featured Articles & Applications

  1. Automated mAb Workflows: Combining Multidimensional (Multi-D) Purifications With Product Analysis
    1/24/2018

    A demonstration of the development of a robust, high-quality, and automated Multi-D chromatography purification utilizing both tandem and multi-column configurations using ChromLab™ Software on an NGC Chromatography System.

  2. Are You Ready For The Future of Biomanufacturing?
    1/19/2018

    As novel medicines become a larger part of the industry's portfolio, it is critical you secure a supply chain and manufacturing processes that produce drugs in a reliable, cost-effective way. 

  3. What’s New in U.S. Biosimilar-Land?
    1/16/2018

    A lot has been promised with the introduction of biosimilars, but can they really deliver a viable alternative treatment to biologics at a substantial savings?

  4. An Innovative Solution To Flexibly Meet Unique Primary Packaging Requirements
    1/4/2018

    A customer enlisted Catalent to support their child-resistant blister packaging requirements for a global Phase III study. A flexible design was created with an integrated blister card that could also support larger study requirements of 1.9 million monthly dosing cards. Through customized commercial blistering equipment a solution was provided that would accommodate the customer’s growing demands for clinical supplies.

  5. Scalable Strategies For Parenteral Dosage Form Selection
    12/29/2017

    Understand the strategies which can be employed at the different stages of development when choosing parenteral dosage forms.

     

  6. WuXi Biologics Creates Next-Generation Continuous Manufacturing Platform
    12/20/2017

    Many biologics companies will partner with a contract development and manufacturing organization that can provide the required expertise and resources as well as flexibility of operations.

  7. Using Quality Tools To Build A Cohesive R&D Environment
    12/15/2017

    Developing products in the life sciences industries is complex. Basic quality tools can be used to streamline the development strategy. These tools can help identify your primary goals and assess potential risks and failure modes to enable agile thinking early in development, where experimental outcomes often indicate the need to alter your development strategy.

  8. Unlock Oral Delivery Potential For Macromolecules With A Parallel Screening Approach
    12/13/2017

    Identifying the optimal formulation and dose form which shows an increase more than 20 times in the oral bioavailability of Salmon Calcitonin.

  9. Developing Oral Dosage Forms: An Approach For Faster Path To Market
    12/11/2017

    How an agnostic and data-driven approach early on can optimize the development pathway to bring the molecule to the market faster.

  10. Harvesting Adherent-Dependent Cells From Nunc Cell Factory Systems Protocol
    12/1/2017

    The Thermo Scientific™ Nunc™ Cell Factory™ system is a large multi-layer unit designed for the culture of adherent cells. The design of a Nunc Cell Factory system is similar to a cell culture flask, therefore, a standard cell harvesting protocol may be used. With minor modifications a standard protocol can be optimized for the unique features of the Nunc Cell Factory system.