FEATURED ARTICLES

• Organ-On-A-Chip Technology Unlocks Patient-Derived Precision Medicine

  Personalized medicine struggles with models that fail to reflect real human biology. Organ-on-a-Chip systems recreate tissue complexity, helping predict patient-specific treatment responses.

• How Isogenic Organ-Chips Are Transforming The Future Of Research

  Modeling the human brain requires more than simplified systems. New approaches that incorporate diverse cell types are improving how researchers study neurovascular function with greater precision.

• The AVATAR Program: Modeling Human Bone Marrow Beyond Earth's Orbit

  As deep space missions return, new research is uncovering how human biology adapts beyond Earth. Advanced tissue models offer fresh insight into bone marrow response, opening new possibilities.

• Building A Human-Centric Future For Biologics Development

  Biologics are advancing rapidly, but complexity challenges traditional models. Gain insight into how human-relevant approaches like NAMs and microphysiological systems are gaining traction.

• A Timeline Of U.S. Actions To Reduce Animal Models In Research

  Policy and scientific validation have aligned to shift drug development beyond animal models. New regulations and technologies are making human‑relevant methods the standard for preclinical research.

• New Approach Methodologies: The Future Of Toxicology And Safety Testing

  NAMs are transforming toxicology with human-relevant, non-animal approaches. Learn what defines a NAM, how these methods work together, and why adoption is rapidly accelerating.

• Advancing Drug Safety And Improving R&D Productivity With The Liver-Chip S1

  Explore how the Emulate Liver-Chip S1 revolutionizes predictive toxicology by mimicking human liver biology, achieving superior sensitivity and specificity.

• A Human-Relevant Model Of The Liver Sinusoid

  This organ-on-a-chip model minimizes drug absorption while maintaining the essential architecture. Explore the specifications of this product engineered to model the human liver.

• Improving Gene Therapy Development With Organ-On-A-Chip Technology

  Explore the current challenges of developing gene therapies, the potential of Organ-on-a-Chip technology, the future of gene therapy, and more.

• Customer Spotlight: Queen Mary University Of London's Centre For Predictive In Vitro Models

  Discover the future of in vitro modeling at the Queen Mary+Emulate Organs-on-Chips Centre and unlock new possibilities in the field of predictive medicine.

• Emulate Endorses The FDA Modernization Act Of 2021

  Learn why removing the mandate for animal testing would enable faster, more efficient, and more humane drug development, all while benefiting both patients and the pharmaceutical industry.

• An Introduction To Organ-On-A-Chip Technology

  Discover how Organ-on-a-Chip technology revolutionizes drug development, overcoming the limitations of traditional models to create more accurate, efficient pathways to life-saving treatments.

• The Future Of Preclinical Animal Models In Drug Discovery

  The paradigm shift from animal to human Organ-Chips in preclinical research offers promising insights and efficiencies, crucial for advancing drug development and reducing human suffering.

• Evaluating CAR T-Cell Therapy Vascular Recruitment, Trafficking, And Killing

  Learn about a more human-relevant platform that enables researchers to assess the trafficking and killing efficiency of immunotherapy as well as the proof-of-concept of immuno-oncology co-therapy.

• Designing The Human Emulation System

  Examine how the Human Emulation System merges cutting-edge Organ-on-a-Chip technology with user-friendly design, paving the way for seamless experimentation and deeper insights into human biology.

• Evaluating On-Target/Off-Tumor Effects Of Cancer Immunotherapies

  A promising class of engineered T-cell engaging bispecific antibodies (TCBs) is revolutionizing cancer treatment, but safety concerns persist. Organs-on-Chips offer a human-relevant solution.

• Exploring Neuroinflammation, Neurodegeneration With A Brain Organ-Chip

  Examine how Organ-on-a-Chip technology, accurately mimicking human neuroinflammation, offers promising human-relevant avenues for neurodegenerative disease research and therapeutic development.

• Studying Gut Inflammation And Barrier Disruption With Organ-On-A-Chip Technology

  See how the Colon Intestine-Chip has been employed to model cytokine-mediated inflammation and barrier disruption in the intestine.

• Recapitulating Inflammation: How To Use the Colon Intestine-Chip To Study Complex Mechanisms Of IBD

  To address the challenges associated with conventional drug development models, a Colon Intestine-Chip has been developed to recapitulate the biology that drives inflammatory bowel disease.

• Predicting Human Liver Damage With A More Accurate In Vitro Hepatotoxicity Assay

  This study explores whether a species-specific, multicellular, in vitro hepatotoxicity assays utilizing Liver-Chips can provide a greater understanding of hepatotoxicity mechanisms than animal models.