A Human-Relevant Liver Model With Minimal Drug Absorption

The Liver-Chip R1 integrates up to four different human cell types within the dynamic microenvironment of the Chip-R1^™ Rigid Chip, the newest offering in the Emulate Organ-Chip line. This Chip-R1 features a durable plastic structure that reduces the absorption of small-molecule drugs while maintaining the stacked, two-channel design of the Chip-S1^® Stretchable Chip. It is particularly effective for evaluating drug toxicity, efficacy, and ADME profiles in a human-relevant context, even for compounds that are prone to absorption by PDMS. Read more to learn about this human-relevant liver model with minimal drug absorption.