Newsletter | October 30, 2025

10.30.25 -- Shift To Confidence: Precision Binding Insights With Spectral Shift Technology

Evaluation Of PROTACs Binary And Ternary Affinities With Spectral Shift

Many cancer targets present hurdles in biophysical characterization, especially for PROTACs. Learn how a Spectral Shift affinity screening platform enables precise measurement of complex interactions, accelerating your development of novel degraders.

 

Ultra-High-Throughput Biophysical Screening Of MEK1

Spectral Shift technology enables rapid, resource-conserving biophysical screening for critical drug targets. A study targeting $\text{MEK}1$ successfully identified and validated multiple high-priority binding hits. Learn how this can accelerate your drug discovery efforts.

 

Achieving Highly Sensitive And Precise Binding Affinity Measurements

Gain highly sensitive, precise binding affinity measurements for membrane proteins without disrupting their native structure. Learn how to stabilize these critical drug targets using detergent-free technology for reliable interaction data.

 

How To Keep Your Degrader Pipeline Moving Forward With Dianthus

Developing PROTACs for undruggable cancer targets requires precise biophysical characterization. Learn how Spectral Shift technology accurately evaluates binary and ternary affinities to provide critical insights into degrader performance.