Cytiva product datasheets, catalogs, app notes

  1. Alkaline Stability Of Modern Protein A Chromatography Resins 7/12/2023

    Explore results from a resin lifetime study with over 150 cycles, using clarified cell harvest in every cycle, which has been performed to evaluate the alkaline stability of three protein A resins.

  2. AAV Full/Empty Capsid Separation Using Mechanistic Modeling 5/1/2023

    In this study, we used mechanistic modeling to investigate how AAV-resin interactions are affected when MgCl2 is used as an elution additive.

  3. Recombinant Protein Purification Optimization With HIC 5/1/2023

    A step-by-step high-throughput process development (HTPD) workflow to determine the optimal resin and initial conditions for hydrophobic interaction chromatography (HIC).

  4. Explore Protein Interactions Beyond Affinity To Boost Your Academic Research 7/20/2022

    Explore how you can simplify research on protein-protein interactions using our SPR systems.

  5. Capture Of Histidine-Tagged Molecules Using Biacore His Capture Kit 10/21/2021

    Find recommendations for immobilization of histidine-tagged molecules (ligands) by capture to an anti-histidine antibody covalently coupled to a sensor chip surface.

  6. Chromatography Method For Purifying Infectious Virus Particles 5/20/2021

    This application note demonstrates a chromatography method for purifying reovirus RNA virus particles using a benchtop chromatography system, HiTrap brand columns, and Capto brand Core 700 resin.

  7. Purifying Tagged Proteins Using A Small And Compact LC System 2/3/2020

    Learn how you can perform routine protein purification in a variety of common applications with ease while efficiently utilizing bench and cold cabinet space with the ÄKTA go.

  8. Epitope Binning: A Critical Step In Antibody Selection 1/31/2020

    Epitope binning immunoassays using surface plasmon resonance (SPR) can and should be deployed in the development of new potential drug candidates. This article discusses how SPR is used to characterize closely related “bins” of mAbs targeting the same epitope of the target protein and how the selection process is used to develop new vaccines, therapeutic antibodies, and diagnostic tools.

  9. EDGE Confocal Imaging Technology 10/9/2019

    Increasingly, scientists are being challenged to study more biologically-relevant model systems, and this often means imaging thick, demanding 3D samples that may also be alive. Read how IRIS and EDGE confocal imaging can offer high contrast imaging of thicker samples.

  10. Converting From ELISA To Biacore SPR Assays 3/27/2019

    This article provides general guidance on how to convert an existing ELISA assay to a Biacore SPR-assay and, by doing so, shows how you can get results in less than half the time compared with ELISA.