Cytiva product datasheets, catalogs, app notes

  1. AAV Full/Empty Capsid Separation Using Mechanistic Modeling 5/1/2023

    In this study, we used mechanistic modeling to investigate how AAV-resin interactions are affected when MgCl2 is used as an elution additive.

  2. Recombinant Protein Purification Optimization With HIC 5/1/2023

    A step-by-step high-throughput process development (HTPD) workflow to determine the optimal resin and initial conditions for hydrophobic interaction chromatography (HIC).

  3. Alkaline Stability Of Fc And VH3 Binding In Protein A Resins 5/1/2023

    In this study, we looked at how different antibody binding sites of a protein A ligand are affected by cleaning in place (CIP).

  4. rAAV Production Using HEK293 Cell Line And Transfection Medium 1/13/2023

    Investigate how using a peak expression cell culture medium in the right bioreactor can promote recombinant protein production and improve the performance of a scalable AAV process.

  5. Establishing A Robust Workflow To Identify High-Performing Clones 1/13/2023

    Cell line development is a complex, labor intensive, and multistep process. Learn about a platform and host cell line that minimize the risk and timeline to develop high-performing clones.

  6. Capture Of Bispecific Antibodies And Removal Of Product-Related Impurities 11/17/2022

    Many antibody variants are prone to aggregation or to forming product-related impurities. Explore the application of a resin with novel selectivity to purify challenging entities.

  7. Generating A Robust Host Cell Line For A Cell Line Development Platform 11/14/2022

    Learn how cell performance within the context of the cell line development workflow was confirmed with the successful isolation of stable, high-producing clones from three model monoclonal antibodies.

  8. Explore Protein Interactions Beyond Affinity To Boost Your Academic Research 7/20/2022

    Explore how you can simplify research on protein-protein interactions using our SPR systems.

  9. Capture Of Histidine-Tagged Molecules Using Biacore His Capture Kit 10/21/2021

    Find recommendations for immobilization of histidine-tagged molecules (ligands) by capture to an anti-histidine antibody covalently coupled to a sensor chip surface.

  10. Chromatography Method For Purifying Infectious Virus Particles 5/20/2021

    This application note demonstrates a chromatography method for purifying reovirus RNA virus particles using a benchtop chromatography system, HiTrap brand columns, and Capto brand Core 700 resin.