Altasciences Featured Articles

  1. Historical Review Of In-Life Data From Studies Utilizing AAVs For Gene Therapy 2/4/2025

    These findings provide valuable insights for optimizing AAV study designs while identifying opportunities to refine and reduce the use of NHPs in preclinical research.

  2. Creation Of A Swine Model Of Oral Angioedema 2/4/2025

    Discover how our novel large animal model for angioedema can advance treatment evaluation and drug absorption studies.

  3. Comparison Of Cardiovascular And Respiratory Parameters In 3 Strains Of Research Pigs 2/4/2025

    In this study, cardiovascular and respiratory parameters of Sinclair Nanopigs™ were compared to those of Göttingen® and Yucatan™ minipigs (n=62, average weight 19±6 kg, age 6.5 months).

  4. Understanding Species Variation In The Occurrence Of Spontaneous Background Eye Lesions 2/4/2025

    To better understand the prevalence of naturally occurring ocular lesions, we reviewed acclimation and pre-test data collected over the past year from rats, mice, NHPs, and dogs at our facility.

  5. Introducing Philippine-Origin Cynomolgus Macaque As A Model In Safety Assessments 2/4/2025

    Supply shortages and rising demand for cynomolgus macaques (Macaca fascicularis) in (bio)therapeutic drug development have led to increased reliance on animals sourced from various regions.

  6. 28-Day Intranasal Toxicity Study Of MMS019 In Sprague Dawley Rats And Dogs 1/27/2025

    Explore the potential of MMS019, a carbohydrate-based antiviral nasal prophylactic, to help prevent virus transmission by targeting SARS-CoV-2 spike proteins with its innovative GCPQ formulation.

  7. Tissue Biopsy Collections In Nonhuman Primates During Toxicology Studies 1/27/2025

    Adopting minimally invasive biopsy procedures in nonclinical safety studies can enhance toxicological and biodistribution assessments without compromising data quality or animal well-being.

  8. Historical Background Data In Juvenile Cynomolgus Monkeys 1/27/2025

    This study underscores the importance of exploring underutilized NHP origins to address the limited availability of juvenile NHPs for evaluating advanced therapeutic products.

  9. Development Of A Novel Early Intervention Stabilization For Abdominal Aortic Aneurysms 1/27/2025

    This study highlights the potential of a proprietary catheter combined with a stabilizing agent to provide a much-needed treatment option for abdominal aortic aneurysms.

  10. Development Of A Canine Prostatectomy Model 1/27/2025

    This canine partial prostatectomy model offers an approach for evaluating new prostate cancer therapeutics, providing a reliable system that mimics human procedures while minimizing complications.