Altasciences Featured Articles

  1. Development Of A Novel Canine Prostatectomy Model 2/4/2025

    See how our refined canine partial prostatectomy model offers a promising approach for studying prostate cancer treatments and testing locally applied therapies.

  2. Proposed Best Practices For Optimizing The Number Of Animals In Toxicology Studies 2/4/2025

    The emergence of new drug modalities, coupled with the limited availability of certain research animal models, underscores the need for continuous evaluation of study designs and technologies that support the reduction of animal use in toxicology studies.

  3. Overcoming The Challenges In The Use Of Vascular Access Buttons™ In Rodents 2/4/2025

    Explore how refinements in vascular access button implementation can enhance catheter patency, reduce complications, and improve data quality in preclinical rodent studies.

  4. Historical Review Of In-Life Data From Studies Utilizing AAVs For Gene Therapy 2/4/2025

    These findings provide valuable insights for optimizing AAV study designs while identifying opportunities to refine and reduce the use of NHPs in preclinical research.

  5. Creation Of A Swine Model Of Oral Angioedema 2/4/2025

    Discover how our novel large animal model for angioedema can advance treatment evaluation and drug absorption studies.

  6. Comparison Of Cardiovascular And Respiratory Parameters In 3 Strains Of Research Pigs 2/4/2025

    In this study, cardiovascular and respiratory parameters of Sinclair Nanopigs™ were compared to those of Göttingen® and Yucatan™ minipigs (n=62, average weight 19±6 kg, age 6.5 months).

  7. Understanding Species Variation In The Occurrence Of Spontaneous Background Eye Lesions 2/4/2025

    To better understand the prevalence of naturally occurring ocular lesions, we reviewed acclimation and pre-test data collected over the past year from rats, mice, NHPs, and dogs at our facility.

  8. Introducing Philippine-Origin Cynomolgus Macaque As A Model In Safety Assessments 2/4/2025

    Supply shortages and rising demand for cynomolgus macaques (Macaca fascicularis) in (bio)therapeutic drug development have led to increased reliance on animals sourced from various regions.

  9. 28-Day Intranasal Toxicity Study Of MMS019 In Sprague Dawley Rats And Dogs 1/27/2025

    Explore the potential of MMS019, a carbohydrate-based antiviral nasal prophylactic, to help prevent virus transmission by targeting SARS-CoV-2 spike proteins with its innovative GCPQ formulation.

  10. Tissue Biopsy Collections In Nonhuman Primates During Toxicology Studies 1/27/2025

    Adopting minimally invasive biopsy procedures in nonclinical safety studies can enhance toxicological and biodistribution assessments without compromising data quality or animal well-being.