Altasciences Featured Articles

  1. Cross-Comparison Of Immunophenotyping Assay Performance In Nonhuman Primates 1/27/2025

    Due to supply constraints of Cambodian NHPs, exploring alternative sources like Philippine and Mauritius-sourced cynomolgus macaques is crucial for maintaining nonclinical safety assessments.

  2. Cross-Comparison Of Biomarker Assay Performance In Nonhuman Primates 1/27/2025

    This presentation compares standard panels, such as cytokines and complements, that are typically evaluated in toxicological studies to determine the viability of these alternative strains.

  3. Clinical Pathology Reference Data For The Philippine Cynomolgus Monkey For Preclinical Toxicology Studies 1/27/2025

    As demand for cynomolgus macaques grows, comprehensive reference data for underutilized origins like Philippine-origin CM is essential for accurate data interpretation in preclinical toxicology programs.

  4. The Sinclair Nanopig™—The Other Non-Rodent 1/27/2025

    Given its close physiological similarities to humans, the minipig should be considered a valuable alternative for nonclinical safety assessments in small molecule and biologic drug development.

  5. Assessing The Safety Of Novel Therapeutics For Pediatric Indications 1/9/2025

    Discover strategies to overcome the challenges of nonclinical testing for pediatric and rare disease therapies, ensuring regulatory compliance and successfully advancing your medicinal products to the clinic.

  6. Safety Assessment Of Intravitreal Implants In Dutch Belted Rabbits 1/9/2025

    Address unique anatomical challenges to deliver reliable, IND-enabling data for innovative therapies by relying on our expertise to design and execute your complex ocular safety study.

  7. Nanosuspension Formulation To Maximize Potency For Preclinical Studies 1/9/2025

    By having a tailored proactive drug development approach, companies can accelerate their API's journey through preclinical development, ensuring the creation of a stable, high-potency formulation.

  8. Overcoming Known Pharmacological Effects 1/9/2025

    Uncover how our team was able to address the challenges of evaluating treatments that reduce food consumption and cause body weight loss while ensuring animal health and study integrity.

  9. Gene Therapy And Stem Cell Transplantation Via MRI-Guided Intraparenchymal Delivery Into Brain Regions 1/9/2025

    This stem cell transplantation technique, using real-time MRI imaging and precise stereotactic guidance, ensures accurate treatment delivery in macaque models for optimal brain region targeting.

  10. Characterization Of The Sinclair Nanopig™ For Biopharmaceuticals Safety Assessment 1/9/2025

    Discover groundbreaking data that supports the use of the Sinclair Nanopig™ to reduce reliance on traditional non-rodent species in drug development, validating its value in drug safety studies.