Newsletter | April 4, 2026

04.04.26 -- Drug Discovery Online Best Of March

MARCH'S BEST FEATURED EDITORIAL

Hibernating Squirrels May Hold Clues To Treating Heart Failure

Examining natural mechanisms of cardiac repair in hibernating squirrels has provided insight into biological pathways that could help develop a therapeutic for HFpEF.

In Vivo LNP-Engineered Cytokine-Armored CAR Cells For Solid Tumors

By injecting lipid-based nanoparticles encapsulating mRNA and encoding the CAR directly into the bloodstream, developers can effectively reprogram the patient's own immune cells in situ.

Charting The Future Of Antimicrobial Resistance

We caught up with Ajit Parhi, Ph.D., CSO of TAXIS Pharmaceuticals, to discuss policy, precision science, and AI in battling antimicrobial resistance.

MARCH'S BEST INDUSTRY INSIGHTS

How GMP And Clinical Rules Shape Upstream Discovery And Development

Early collaboration between R&D and manufacturing ensures regulatory readiness and efficiency. Learn how automation and robust panel design enable clinical translation for advanced development.

A Pragmatic Approach To Developing A Rare Disease Drug

We are beginning to see a rise in the interest of “orphan drugs." Discover challenges and considerations associated with the expedited development and how to successfully work through them.

Residual iPSC And Genomic Stability Testing With High Multiplex Digital PCR

Sensitive digital PCR methods enable confident detection of low‑abundance iPSC markers. Gain insight into how these capabilities support more reliable monitoring and quality assessment.

MARCH'S BEST SOLUTIONS

How Can We Make Drug Discovery Faster And Smarter?

PBPK Predictive Modeling Services

Automated, Single-Use Systems For TFF At Multiple Scales