Cytiva product datasheets, catalogs, app notes

31. An End-To-End, Semi-Continuous Process For mAb Production 9/22/2019

    See how the different unit operations in a laboratory-scale monoclonal antibody (mAb) process can be connected and integrated into a semi-continuous process.

32. Quantitating Binding Similarities In IgG Fcγ Receptor Analysis 5/23/2019

    Critical quality attributes are fundamental to regulatory compliance in drug development and manufacturing. Learn how surface plasmon resonance has been applied for protein characterization of antibody effector function.

33. Converting From ELISA To Biacore SPR Assays 3/27/2019

    This article provides general guidance on how to convert an existing ELISA assay to a Biacore SPR-assay and, by doing so, shows how you can get results in less than half the time compared with ELISA.

34. Adenovirus Production In Single-Use Bioreactor System 3/8/2019

    Rocking bioreactor systems can shorten the seed train prior to inoculation and provide optimized growth conditions for sensitive cells. This study presents a robust production of adenovirus using such a system.

35. Multidimensional Scale-Up Of A mAb Capture Step Contributes To Shortened Time To Market 10/10/2018

    This application note demonstrates a multidimensional scale-up (change of both column diameter and bed height) of a mAb capture step, using the ÄKTA pilot 600 chromatography system.

36. Process-Economy Simulation Of mAb Capture Step With Protein A Chromatography Resin 10/10/2018

    Calculation examples that highlight scenarios where the enhanced capacity and alkaline‑stability of MabSelect PrismA can provide process economic benefits to large‑scale mAb processing.

37. Use Of Sodium Hydroxide For Cleaning And Sanitization Of Chromatography Resins And Systems 10/2/2018

    This application note examines these aspects of using sodium hydroxide as a cleaning and sanitizing agent.

38. Capacity And Performance Of MabSelect™ PrismA Protein A Chromatography Resin 10/2/2018

    This application note demonstrates the binding capacity of MabSelect PrismA in comparison with its predecessor products for both polyclonal and monoclonal antibodies.

39. Downstream Process Development For Efficient Purification Of Adenovirus 9/10/2018

    Here, we describe the development of two effective downstream processes for purification of adenovirus from cell culture harvest.

40. Optimization Of Midstream Cell Lysis And Virus Filtration Steps In An Adenovirus Purification Process 9/10/2018

    Here we describe screening of detergents for release of adenovirus from HEK293 host cells to replace the traditionally used detergent Triton™.