06.06.26 -- Drug Discovery Online Best Of May

Protein design has advanced faster than small‑molecule AI. Small‑molecule modeling faces a much larger chemical space and far less openly available data, much of which remains tied to proprietary pharma programs.

We caught up with Melissa Murray, Ph.D., and Amy Rommel, Ph.D., to discuss tau-associated neurodegenerative diseases.

Speaking from a microbiologist’s perspective rather than as an AI expert, join Jon Stokes as he discusses the practical realities of small‑molecule antibiotic discovery.

Examine how 780 human Liver-Chips were assessed for their ability to predict drug-induced liver injury from small molecules.

Gene therapy holds promise for treating various genetic diseases. Explore the latest in gene therapy with expert insights on AAV vector integrity, dPCR-based solutions, and assay design.

Metabolic pathways define immune cell roles, from glycolysis fueling inflammation to fatty acid oxidation sustaining memory and tolerance. Discover how energy metabolism shapes immune responses.