ABOUT US
X-Chem is redefining small molecule drug discovery through a powerful combination of computational sciences, discovery chemistry and data-driven insight. As the pioneer and global leader in DNA-encoded library (DEL) technology, X-Chem provides the foundation for smarter hit identification, accelerated lead progression and greater confidence in early discovery.
Learn more at www.x-chemrx.com.
FEATURED ARTICLES
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![GettyImages-2181934436-laboratory-analysis-scientists-technology-computer]( "Translating Massive Data Into Therapeutic Momentum")
New advances in chemomics, proteome mapping, and modern synthetic methods are redefining how quickly and precisely discovery teams can move from raw data to meaningful clinical momentum.
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![GettyImages-1347856181 assay, pipette]( "Covalent Warhead Reactivity: A New Look At GSH Reactivity Assays")
Understanding covalent warhead kinetics is key to reducing safety risks early in discovery. Learn about a new approach to GSH‑based measurements that offers clearer predictors of toxicity.
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![GettyImages-1440940383-chemical-bonds-3d-structure]( "Flow Chemistry For Contemporary Isotope Labeling")
Gain insight into how late‑stage exchange and flow‑based methods enable efficient access to labeled molecules for pharmaceuticals, mechanistic studies, and analytical applications.
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![dna, rna molecules-GettyImages-537327406]( "Mirror, Mirror Makes RNA-targeted Discovery Smarter")
Examine a mirror‑image screening approach that eliminates DNA:RNA hybridization, revealing true binders and unlocking clearer, more productive DEL results for challenging RNA targets.
CONTACT INFORMATION
X-Chem
100 Beaver Street, Suite 101
Waltham, MA 02453
UNITED STATES
Contact: Lisa Yoder
FEATURED VIDEOS
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![What Matters More In DNA-Encoded Libraries]( "What Matters More In DNA-Encoded Libraries?")
DELs can screen billions of compounds, but library quality determines meaningful results. See how thoughtful design shapes early decisions that influence which drug candidates move forward.
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![Unlocking Chemomic Insights For Drug Discovery]( "DNA-Encoded Library Data: Unlocking Chemomic Insights For Drug Discovery")
Discover how chemomic analysis unlocks full DEL datasets to reveal early SAR trends, mechanism clues, and risks to help teams make clearer, data‑driven decisions and build stronger hit‑to‑lead foundations.
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![Drug Discovery Beyond Rule Of Five ECCS Class 3 And 4 Strategies]( "Drug Discovery Beyond Rule Of Five: ECCS Class 3 And 4 Strategies")
Gain practical guidance for advancing bRo5 candidates through improved permeability and metabolic stability with insights on ECCS classes 3 and 4, optimized in vitro tools, and design principles.
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![Combing Artificial Intelligence And DNA-Encoded Libraries]( "What Are The Benefits Of Combing AI And DELs For Drug Discovery?")
Discover how AI-powered modeling uncovers hidden patterns in DEL data, broadens chemical diversity, and accelerates decision-making to help teams prioritize compounds and move more efficiently.
FEATURED SOLUTIONS
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![Chemomics_Spotlight_Interview]( "How Can We Make Drug Discovery Faster And Smarter?")
DEL technology is evolving from a screening tool into a rich data engine for AI. Learn how expanding datasets and computational methods are reshaping what researchers can uncover.
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![DEL]( "Discover Our DNA-Encoded Library (DEL) Technology")
Discover how DNA barcoding enables rapid screening of vast chemical space in early drug discovery, as well as how DEL platforms test billions of compounds efficiently.
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![DNA double helix,Human DNA-GettyImages-1912348507]( "Small Molecule Exponential Discovery")
Explore how a data‑driven discovery model combines DEL screening, computational insights, and medicinal chemistry to accelerate hit‑to‑lead decisions, reduce risk, and enable efficient progression.
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![GettyImages-474436406-chemical-equations-bonds]( "Turning Screening Data Into Discovery Direction")
Chemomics transforms full DEL datasets into predictive insights. See how combining large-scale screening with clear computational models accelerates SAR understanding and strengthens confidence.
