The EntoEngine: Fruit Flies For Advanced Biomanufacturing
Produce recombinant proteins at scale with stable expression, flexible batch sizes, and streamlined manufacturing.
Using Drosophila melanogaster as the expression host, our first-of-its-kind EntoEngine® combines genetic engineering with insect farming to produce recombinant proteins at scale.
Reinventing recombinant protein production.
Using Drosophila melanogaster as the expression host, our first-of-its-kind EntoEngine® combines genetic engineering with insect farming to produce recombinant proteins at scale.
Key Advantages
Multicellular Expression
200+ distinct cell types with the genetic tools to selectively target expression–all in one platform
Inducible Expression
Robust, efficient, and pharma-safe inducible expression at scale, unlocking toxic protein production
Unparalleled Scaling Potential
Cost-effective and flexible, offering custom batch sizes from micrograms to grams
Genetic Stability
Long-term stability of expression strains means clients can receive quality proteins on-demand
Why flies?
E. coli and yeast offer speed and flexibility, but lack robust scale-up production capabilities.
This creates the need for stable cells lines, which results in a significant timeline bottleneck.
The EntoEngine® eliminates trade-offs and bottlenecks with stable protein expression for large-scale commercial manufacturing.