Newsletter | May 19, 2026

05.19.26 -- From Urine-Derived To Recombinant Precision: KLK1 Reimagined For Preeclampsia

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Helping ensure safer immunotherapies: From gene editing to next-generation sequencing (NGS)-based T cell characterization

Discover how gene-edited T cells are reshaping cancer immunotherapy in this Qiagen webinar. Explore how targeting PD-1 and TIGIT may enhance anti-tumor activity, while integrated genomic workflows and NGS-based transcriptomic profiling support deeper functional insights. Learn how advanced cell engineering and automated sample prep are accelerating cell therapy discovery, characterization, and lead development. Click here to learn more.

FEATURED EDITORIAL

From Urine-Derived To Recombinant Precision: KLK1 Reimagined For Preeclampsia

DiaMedica is testing a synthetic, first-in-class recombinant human kallikrein‑1 (rhKLK1) biologic in Phase 2 clinical trials to treat preeclampsia, which remains one of the most dangerous complications of pregnancy.

MicroRNA Therapeutics In Metabolic Liver Disease: Context-Driven Drug Discovery

Realizing the therapeutic potential of miRNAs in liver disease requires confronting a problem the field has not fully reckoned with.

Proteomics Biomarkers Beyond Blood

Effective biomarker strategies have the potential to accelerate decision-making, de-risk development, and help drive precision medicine.

INDUSTRY INSIGHTS

Everything You Need To Know About NGS

Next generation sequencing technologies and workflow automation are accelerating genomic research. Learn key differences between sequencing methods and uncover strategies to boost efficiency.

Metabolic Pathways And The Immune System

Metabolic pathways define immune cell roles, from glycolysis fueling inflammation to fatty acid oxidation sustaining memory and tolerance. Discover how energy metabolism shapes immune responses.

Diagnose Absorption Risks To Improve Preclinical And Clinical Outcomes

Physiologically based pharmacokinetic modeling is a powerful tool for clinical trial design that can be leveraged alongside early development experiments to reduce costs and accelerate timelines.

Crystallization Of Challenging Pharmaceutical Targets To Aid Drug Discovery

Explore a few successful strategies used when growing crystals of challenging pharmaceutical targets to aid drug discovery, and two case studies performed by an experienced team of crystallographers.

Decoding ADC ADME With Tailored Strategies

Overcome the complex ADME and DDI challenges of antibody–drug conjugates with tailored, data-driven strategies that accelerate development and support regulatory success.

What Matters More In DNA-Encoded Libraries?

DELs can screen billions of compounds, but library quality determines meaningful results. See how thoughtful design shapes early decisions that influence which drug candidates move forward.

Simultaneous Spray Drying For Combination Dry Powder Formulations

Three combination case studies are demonstrated, in which bevacizumab is paired with erlotinib, cisplatin, or paclitaxel in a dry powder inhaler formulation.

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Register for the Pharmaceutical Online Live event on May 27, at 11am Eastern for Analytical Strategies for High-Volume GLP-1 Manufacturing. The talk will highlight opportunities to improve scalability through automation and streamlined method platforms, positioning analytics as a central enabler of reliable, high-volume GLP-1 manufacturing. This virtual discussion will be moderated by Chief Editor Katie Anderson and is completely free to attend thanks to our sponsors Waters Corp. and Agilent.

SOLUTIONS

A Consumable Empowering High-Throughput Organ-Chip Studies

Automated, Single-Use Systems For TFF At Multiple Scales