Early Developability And Analytical Toolbox For The Production Of Multi-Chain Biotherapeutics

In recent years the number of biotherapeutic molecules requiring more complex assemblies has greatly increased. Typically, these multi-chain molecules are no longer compatible with platform approaches and require a more agile approach to early developability and method development. Lonza have developed a Toolbox approach using in silico tools, vector design/screening and analytical method development that allows us to screen for titre and product assembly at an early stage of development.