Mixing is a critical operation within many biopharmaceutical processes for applications ranging from buffer and media preparation, in-process unit operations such as low pH viral inactivation, to final formulation. The Allegro 50 L single-use mixer is part of Pall’s expanding range of Allegro products and services providing integrated process solutions throughout the drug production process. The Allegro mixers combine critical requirements for single-use technologies, such as extreme ease-of-use, with established engineering design principles and criteria for robust mixer design to deliver the ultimate in mixing performance. The 50 L mixer is a scale down version of the larger mixers in the Allegro range (200 L, 500 L and 1000 L) with the additional feature of an advanced impeller design to facilitate low volume mixing down to 2 L.
The standard model of the Allegro 50 L mixer incorporates a plastic tote. As with the other mixers in the range, the mixer is also available in a jacketed stainless steel tote format, and can incorporate sensors (e.g. pH, conductivity and temperature) for on-line monitoring and control.
Sensor signals can be displayed locally on the mixer, or alternatively, can be connected to an automated Allegro MVP system. With the added capability of a Weighing Platform option, the Allegro mixer from Pall can be fully integrated to the Allegro MVP automated single-use system, providing complete automated process monitoring and control solutions for all applications that require mixing (e.g pH adjustment for buffers and virus inactivation).