Accelerating Structure Verification Across Novartis

High-throughput NMR environments demand speed without sacrificing confidence in structural assignments. An automated structure verification workflow embedded directly into open-access NMR operations shows how routine confirmation can be streamlined across hundreds of users and instruments. By dynamically adjusting experiment parameters based on sample quality and automatically validating proposed structures, chemists receive processed data and verification reports with minimal manual intervention. Performance data from a representative day highlights where automation excels, where false negatives arise, and why these outcomes still reduce downstream workload. The impact becomes especially clear in pharmaceutical development, where experienced analysts can shift time away from routine checks toward complex structure elucidation. Ongoing refinements—including improved experiment calibration and richer prediction models—point to even greater accuracy and efficiency gains ahead.

Explore how scalable automation reshapes everyday NMR verification and what it means for productivity in modern discovery and development labs.