By Sachin Mangale,Syngene International Ltd.
Proteolysis-targeting chimeras (PROTACs) and other protein degradation strategies offer benefits in drug discovery for challenging targets. Discover considerations when launching a PROTAC development program.
Size exclusion chromatography is the go-to analytical method for therapeutic protein drugs. This article describes the factors affecting the reproducibility of columns and how you can minimize column variation.
This application note demonstrates systems that have proven quite useful for clarification of mammalian cell cultures such as CHO-cells by combining the cell clearance and sterile filtration functionality in a single device.