Featured Articles

  1. 6 Misconceptions About Automating Cell Therapy Manufacturing 6/18/2020

    To help you move into a digitized world, here are six common misconceptions that can potentially hinder your ability to successfully execute an MES for cell therapy.

  2. Standardizing Vein-To-Vein Logistics To Reach More Patients 2/24/2020

    Collaboration is  key to solving data management and process variability challenges as stakeholders work towards a common goal—getting life-saving treatments to those who need them.

  3. Automating Cell Therapy Systems For Better Results 2/23/2020

    Cell therapy treatments are often made at a small-scale, require days of manual preparation, and are usually produced for use in a clinical trial. What if it were possible to get results on a much broader scale?

  4. LV Scale-Up Workflow In Single-Use Bioreactors For GMP Compliance 11/8/2019

    Cost-effective manufacturing of lentiviral vectors (LV) at commercial scales has proven difficult and remains a pressing issue for the marketing of therapies that depend on their application.

  5. Viral Clearance: The Basics On How To Conduct Effective Studies 5/17/2019

    Effective viral clearance studies remain one of the challenges facing manufacturers of biologics. These studies are an essential part of process validation and are critical to ensure drug safety. This article provides the basics of what you need to know when studying virus reduction of a chromatography step.

  6. Freezing Cellular Raw Materials For Cell Therapy Production 3/5/2019

    Key Biologics is harnessing new freezing technology to help deliver the future of medicine. Digitally enabled cryogenic cold chain technology can now deliver the raw materials needed to manufacture cellular therapies.

  7. Effective Separation Of Full And Empty AAV Capsids By Anion Exchange

    We show how Capto Q resin with dextran surface extenders, magnesium chloride (MgCl2), and the elution salt type (especially for rAAV9) significantly enhance separation.