
ABOUT ALTASCIENCES
Altasciences transforms the traditional outsourcing paradigm by simplifying and streamlining drug development solutions, whether for a single study or multiple programs, to offer an integrated/synchronized approach to CRO and CDMO services.
FEATURED CONTENT
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Consider the potential of Sinclair Nanopig™ as a next-generation non-rodent model to enhance drug development, improve regulatory pharmacology, and reduce reliance on traditional non-rodent models.
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Ultrasound-guided liver biopsies offer a safe, minimally invasive method for repeated tissue collection in non-human primates, ensuring reliable results with minimal animal stress and recovery time.
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Support the development of standardized SEND guidelines for Animal Rule studies to ensure accurate and consistent regulatory submissions for acute radiation syndrome research.
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A robust LC-MS/MS assay to quantify CTI-1601 in cynomolgus monkey tissues is essential for understanding its disposition and processing, supporting its potential as a protein replacement therapy.
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For accurate immunotoxicity assessment, cytokine data should be interpreted alongside clinical observations, body weight, and clinical pathology parameters.
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Consider our robust and reproducible method for detecting Foxp3+ Tregs in cynomolgus monkeys, which enables a more effective evaluation of immunotherapies targeting Treg modulation.
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Explore how housing conditions impact stress levels in non-human primates and their relevance to toxicology studies, highlighting the potential benefits of gang housing.
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Explore the potential of the cynomolgus monkey model with IL-31 pruritus to advance research and development of effective treatments for atopic dermatitis and other pruritic skin diseases.
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Leverage TEG alongside conventional hematology to enhance the evaluation of coagulation disorders and provide more comprehensive insights into drug development and bleeding disorders.
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Explore the feasibility and efficiency of using a single assay coupled with LC-MS/MS for quantifying Pirfenidone and its metabolites in rat plasma, ensuring precision, accuracy, and separation.
CONTACT INFORMATION
Altasciences
6605 Merrill Creek Parkway
Everett, WA 98203
UNITED STATES
Contact: contact@altasciences.com
FEATURED SOLUTIONS
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Altasciences specializes in lead optimization studies, helping you identify the most promising drug candidates through precise, data-driven preclinical screening. Our expert scientists tailor each study to your unique needs, utilizing efficient non-GLP screening protocols to accelerate decision-making. With streamlined study designs, clear data visualization, and rapid turnaround times, we provide actionable insights to advance your drug discovery pipeline.
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With over 130 in-life gene therapy studies completed, Altasciences is a leading expert in gene therapy research, with integrated preclinical and bioanalytical capabilities.
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We maintain an unwavering focus on the welfare of the laboratory animals in our care. Our entire preclinical staff is trained in laboratory animal care and focused on animal welfare and environmental enrichment — embracing compassion, sensitivity and adherence to regulatory guidelines.
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Preclinical immunotoxicology studies play a crucial role in assessing the potential adverse effects of drugs, chemicals, or other substances on the immune system before they advance to first-in-human linical trials.
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Safety pharmacology is the cornerstone of responsible drug development. It involves the evaluation of a drug candidate's potential impact on vital organ systems such as the cardiovascular, respiratory, and central nervous systems. By identifying any potential safety concerns early in the development process, safety pharmacology studies play a crucial role in minimizing risks to patients and ensuring the overall safety and efficacy of the final product.
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Leveraging extensive expertise and state-of-the-art facilities, Altasciences conducts comprehensive toxicology evaluations to ensure the safety and regulatory compliance of your novel drug candidates.
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The miniature swine continues to develop as a viable non-rodent option for nonclinical studies. With the increase of historical data and wider regulatory acceptance, the miniature swine model can support a variety of research areas. Their availability, physiological similarities to humans, and lower cost compared to other non-rodent models makes miniature pigs an advantageous option for nonclinical programs. However, it is essential that scientific rationale is the driving factor when selecting species for your study.
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Industry leader in preclinical safety assessments across various therapeutic areas. 30+ years of experience in full range of in vivo non-GLP and GLP studies in both rodent and non-rodent species.
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Partner with us to accelerate your drug development journey, from lead candidate selection to proof of concept, with our comprehensive, globally compliant preclinical, clinical, and manufacturing solutions.
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Species selection for preclinical studies should be based on solid scientific rationale. Our experts will assess all available data to guide you in making a well-informed, appropriate choice.