Newsletter | October 3, 2023

10.03.23 -- Targeting RNA With Small Molecules

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FEATURED EDITORIAL

Targeting RNA With Small Molecules

Beyond mRNA's dogmatic role as the intermediate in gene expression, noncoding RNA play essential roles in transcription regulation, maturation, and translation. This article explores the potential of RNA as a clinically validated avenue for drug development, methods for design and discovery, and implications for the future of medicine.

INDUSTRY INSIGHTS

Fixed-Dose Combination Drugs

A company was seeking a CDMO partner with the expertise and technological capabilities to combine three drug substances into a fixed-dose combination product suitable for adult and pediatric dosing.

Ultra-High Potency Development And Manufacture

A biotech with limited experience in the development and manufacture of high potency compounds sought to develop a process for producing a highly potent API used to treat an unmet oncology need.

Developing Biosimilars: Challenges And Solutions

Biophysical characterization requires technologies that often require expensive reagents, large quantities of samples, and experimental conditions optimization. Simplified analytical workflows can help.

Increase Spray Drying Throughput For Brick Dust Compounds

We discuss three enabling technologies designed to improve drug solubility in organic solvents for spray drying and define the advantages and risks of each technology.

Local Delivery For Treatment Of Lung Cancer

Explore two case studies where lung cancer therapies were delivered to the lung by dry powder inhaler in a rat model and evaluated for efficacy, confirming local delivery is a promising route to treat lung cancer.

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Twist Bioscience & IMIDomics Collab To Discover Antibodies For Applications In IMIDs

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Ono Enters Into A Drug Discovery Collaboration Agreement With Adimab

SOLUTIONS

Surfactant Analysis Services

Addressing Some Of The Most Common Surface Plasmon Resonance Questions

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