Application Note

Simplifying Large Scale Single-Use Filtration While Decreasing Risk With A Novel Modular Approach

Source: Sartorius

By Andre Grebe and Dr. Florian Mieth


Filtration plays a critical role in assuring the safety and quality of biopharmaceutical products. Stainless steel multi-round housings are commonly used in conventional large-scale filtration processes, while filter assemblies with multiple components and connections provide a single-use alternative. Single-use systems offer flexibility and speed in the production of pharmaceuticals and vaccines. Large-scale production increases material consumption (due to the increased number of components involved), process complexity, and associated risks. To meet these challenges, Sartorius developed a modular platform-based approach called Maxicaps® MR that offers a simplified, standardized design with integrated functionality for large-scale filtration applications in protein- and virus-based therapy production processes.

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