Newsletter | December 17, 2024

12.17.24 -- Should We Explore Suicidality In Animals During Preclinical Drug Development?

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FEATURED EDITORIAL

Should We Explore Suicidality In Animals During Preclinical Drug Development?

An adverse side effect for some drugs is suicidal ideation and behavior (SIB). Investigating SIB in animal studies represents the closest approximation to human SIB, yet the FDA Modernization Act 3.0 obligates us to reduce unnecessary animal testing. Let's examine this with data-driven research.

INDUSTRY INSIGHTS

Utilizing Nanoparticle Technologies For A More Sustainable Value Chain

The pharma industry is identifying ways to make processes more sustainable. Learn how nanoparticle engineering technology can both empower sustainability goals and lead to better patient outcomes.

Approaching IND: What To Consider In Early Development

When preparing for IND submission, developers must consider multiple components. Explore tips for optimizing your early development program and the benefits of housing all activities under one roof.

Following The Science To Develop Best-In-Class Cancer Drugs

As innovative cancer therapeutics continue to enter the clinical trial pipeline, some developers are shifting their focus toward developing drugs that are safe and efficacious with minimal toxicity.

Trends In Next-Generation Delivery Technologies

Learn how lipid nanoparticles are enabling a new generation of engineered cell therapies with a push toward more complex cell engineering and gene editing for allogeneic therapies.

Resource Roadmap To Screening Success

Explore how tools streamline the development of cell-based therapies by optimizing processes, reducing costs, and accelerating manufacturing scalability. 

Early Solid Form Screening To Guide Drug Development

Conducting solid form screening early can help your team select and isolate the ideal lead polymorph to ensure manufacturability and stability while avoiding costs and hiccups down the road.

Simultaneous Spray Drying For Large/Small Mol Combinations

Gain insights into a “simul-spray” process pioneering for combining small and large molecules into a single, atomized drug product for inhalation administration.

Resource Savings Through Effective Global Trade Compliance

Ensure consistent planning, accurate cost estimation, and enhanced delivery timelines for materials shipped across borders by partnering with a CDMO equipped with a dedicated trade compliance team.

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