07.13.23 -- Improving Environmental Sustainability In The Pharmaceutical Industry

Learn more about Lonza’s approach to sustainability, including the methodology used for solvent recovery and how solvent recovery can lead to significant CO₂ reductions. Review the methods used to evaluate, design, and implement solvent recovery processes, along with the substantial CO₂ reductions that Lonza has been able to achieve and how they’re measured.

As leaders strategize to develop greener pharmaceutical processes and reduce carbon footprints, some are designing innovative techniques for reducing waste, carbon emissions, and energy usage throughout the manufacturing process. At Lonza, wastewater incineration reduction and solvent recovery initiatives have helped to yield notably greener results.

Spray drying is a commonly used process for producing amorphous solid dispersions (ASDs) of drugs that are poorly water soluble. Using volatile processing aids to increase drug solubility in more environmentally friendly solvents, like methanol, reduces negative environmental impacts and the amount of solvent required to manufacture ASDs.

The growing complexity of the small molecules entering, and progressing through, the pharmaceutical pipeline throws the need for manufacturing expertise and experience into sharp focus. The support of an experienced CDMO is critical to overcoming complexity when working with a HPAPI and when solving solubility challenges.