News | September 5, 2018

Yumanity Therapeutics Announces First Clinical Candidate For The Potential Treatment Of Parkinson's Disease

First-in-human trials planned for the fourth quarter of 2019; IND-enabling studies to be completed utilizing Evotec INDiGO platform

Yumanity Therapeutics, a company focused on discovering transformative therapies to treat neurodegenerative diseases, recently announced its lead clinical candidate, YTX-7739, is entering IND-enabling studies for the treatment of Parkinson’s disease and related disorders. YTX-7739 is a novel therapeutic, focused on a novel target newly identified to play a role in Parkinson’s Disease discovered using Yumanity Therapeutics’ proprietary drug discovery platform. YTX-7739 is expected to enter first-in-human studies by the fourth quarter of 2019.

“In two short years, the team at Yumanity has made unprecedented progress advancing our lead program to development stage candidate,” said Ken Rhodes, Ph.D., chief scientific officer, Yumanity Therapeutics. “Our proprietary discovery platforms have revealed novel targets and therapeutic approaches to neurodegenerative diseases, enabling us to bring YTX-7739 forward for development on an accelerated timeframe. We’re excited to initiate our collaboration with Evotec, leveraging the strength of their INDiGO platform to begin development of YTX-7739.”

Evotec will apply their industry-leading INDiGO platform to support clinical development of YTX-7739. The INDiGO platform is a component of Evotec’s broad EVT Execute business strategy and accelerates drug candidates into the clinic by reducing time from nomination to IND submission to 52 weeks or less. Accelerated development is achieved by tightly integrating traditional drug development activities into a single project managed under one roof.

Source: Yumanity Therapeutics