03.25.25 -- Understanding The New U.K. MHRA 'Draft Guideline On Individualised mRNA Cancer Immunotherapies'

Here, we present a hybridoma-based antibody discovery and humanization strategy for a T1P target, utilizing Penta Mice immunization to generate monoclonal antibodies.

Testing for nitrosamines is essential in the development and manufacturing of Active Pharmaceutical Ingredients (APIs) and drug products to ensure safety and compliance.

Equip yourself with the knowledge necessary to make well-informed decisions by exploring the main challenges and considerations inherent in cell therapy process development.

Review the role of solid form screening and PBPK modeling to enable accelerated timelines desirable in early-phase drug development. Explore formulation maps for ASDs and key criteria for salt screening.

Spray drying of amorphous dispersions improves solubility and bioavailability, enabling supersaturation in the intestine and driving higher absorption rates when compared to crystalline drug forms.

See how Cube Biotech and MIT researchers used dynamic light scattering (DLS) and nano differential scanning fluorimetry (nanoDSF) to find the best nanodisc conditions for three membrane proteins.