In this study, we used capture with weak anion exchange and optimized the Capto™ Core 700 chromatography resin polishing step to maximize infectious recovery.
Cytiva scientists lend their insights from two years’ work. Includes upstream, downstream, and analytics. Get details on baseline separation of empty and full capsids with a single chromatography resin and buffer for multiple recombinant AAV serotypes.
AGC Biologics discusses their journey to successful implementation of iCELLis™ bioreactors in their AAV and lentivirus platforms. These bioreactors are used in several commercial processes for viral vector manufacturing in adherent cells.