Developing a robust manufacturing process is crucial for any drug developer, requiring comprehensive evaluation of both upstream and downstream steps to achieve end-to-end process insight across the entire production workflow. Learn more about how such a process ensures the safety and efficacy of mRNA-LNPs.
Explore how lipid nanoparticles (LNPs) are advancing gene-modified cell therapies by enabling more complex cell engineering, highlighting their potential and the need for scalable, efficient delivery technologies.
This application note outlines a method utilizing RNA-LNPs for highly efficient genome editing of human primary T cells while maintaining high cell viability and demonstrates its potential to enhance CAR T cell therapies through CRISPR/Cas9-mediated gene editing.
Learn about the strategies and technologies for accelerating the development and scale-up of mRNA vaccines, emphasizing the importance of efficient production processes and advanced delivery systems to meet global healthcare demands.
Gain insight into how the NanoAssemblr™ Ignite™ systems utilize NxGen™ mixing technology for precise, reproducible, and scalable lipid nanoparticle (LNP) manufacturing, simplifying workflows and ensuring consistent quality in preclinical genomic medicine development.
