Productivity In mAb Capture

As therapeutic antibodies continue to evolve, advancements in their production processes are becoming increasingly focused on enhancing both cost efficiency and productivity across all stages of development and manufacturing. One critical area of improvement is monoclonal antibody (mAb) capture chromatography, a key step in the purification process. In this video, we explore strategies to optimize this step, with particular attention to selecting the most suitable resins for purification. The discussion emphasizes how resin choice can significantly impact overall process efficiency, especially when considering variables such as the stage of drug development, scale-up requirements, batch sizes, and production frequency. By evaluating a range of real-world scenarios, the video illustrates how different protein A resins can offer distinct advantages depending on the specific needs of the process. These insights help guide decisions that balance productivity, cost, and processing time, ultimately supporting more efficient and scalable therapeutic antibody production.

Learn more about our protein A resins: https://www.cytivalifesciences.com/solutions/bioprocessing/products-and-solutions/downstream-bioprocessing/protein-a-chromatography-solutions